Synchronization-induced spike termination in networks of bistable neurons Torres Agudo, Joaquín Uzuntarla, Muhammet Bianconi, Ginestra We observe and study a self-organized phenomenon whereby the activity in a network of spiking neurons spontaneously terminates. We consider different types of populations, consisting of bistable model neurons connected electrically by gap junctions, or by either excitatory or inhibitory synapses, in a scale-free connection topology. We find that strongly synchronized population spiking events lead to complete cessation of activity in excitatory networks, but not in gap junction or inhibitory networks. We identify the underlying mechanism responsible for this phenomenon by examining the particular shape of the excitatory postsynaptic currents that arise in the neurons. We also examine the effects of the synaptic time constant, coupling strength, and channel noise on the occurrence of the phenomenon. (C) 2018 Elsevier Ltd. All rights reserved. 2021-10-04T10:24:12Z 2021-10-04T10:24:12Z 2019-02 journal article Torres, JJ; Uzuntarla, M; Bianconi, G. Synchronization-induced spike termination in networks of bistable neurons Neural Networks Volume 110, 131-140 http://hdl.handle.net/10481/70613 10.1016/j.neunet.2018.11.007 eng http://creativecommons.org/licenses/by-nc-nd/3.0/es/ open access Atribución-NoComercial-SinDerivadas 3.0 España