Green Tea and Its Relation to Human Gut Microbiome Pérez Burillo, Sergio Navajas Porras, Beatriz López Maldonado, Alicia Hinojosa Nogueira, Daniel José Pastoriza de la Cueva, Silvia Rufián Henares, José Ángel Green tea Gut microbiota Catechin Polyphenols Health This work was supported by the European Research Commission (Research Executive Agency) under de research project Stance4Health (Grant contract N degrees 816303) and by the Plan propio de Investigacion y Transferencia of the University of Granada under the program "Intensificacion de la Investigacion, modalidad B". This manuscript was also supported by the posdoctoral fellowship granted to S.P.B. under the University of Granada program "Perfeccionamiento de Doctores". Green tea can influence the gut microbiota by either stimulating the growth of specific species or by hindering the development of detrimental ones. At the same time, gut bacteria can metabolize green tea compounds and produce smaller bioactive molecules. Accordingly, green tea benefits could be due to beneficial bacteria or to microbial bioactive metabolites. Therefore, the gut microbiota is likely to act as middle man for, at least, some of the green tea benefits on health. Many health promoting effects of green tea seems to be related to the inter-relation between green tea and gut microbiota. Green tea has proven to be able to correct the microbial dysbiosis that appears during several conditions such as obesity or cancer. On the other hand, tea compounds influence the growth of bacterial species involved in inflammatory processes such as the release of LPS or the modulation of IL production; thus, influencing the development of different chronic diseases. There are many studies trying to link either green tea or green tea phenolic compounds to health benefits via gut microbiota. In this review, we tried to summarize the most recent research in the area. 2021-07-30T07:58:33Z 2021-07-30T07:58:33Z 2021-06-26 info:eu-repo/semantics/article Pérez-Burillo, S... [et al.]. Green Tea and Its Relation to Human Gut Microbiome. Molecules 2021, 26, 3907. [https://doi.org/10.3390/molecules26133907] http://hdl.handle.net/10481/69989 10.3390/molecules26133907 eng info:eu-repo/grantAgreement/EC/H2020/816303 http://creativecommons.org/licenses/by/3.0/es/ info:eu-repo/semantics/openAccess Atribución 3.0 España MDPI