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   <ow:Publication rdf:about="oai:digibug.ugr.es:10481/68723">
      <dc:title>The Role of Exosomes Derived From Mesenchymal Stromal Cells in Dermatology</dc:title>
      <dc:creator>Quiñones Vico, María Isabel</dc:creator>
      <dc:creator>Sanabria de la Torre, Raquel</dc:creator>
      <dc:creator>Sánchez Diaz, Manuel</dc:creator>
      <dc:creator>Sierra Sánchez, Álvaro</dc:creator>
      <dc:creator>Montero Vilchez, Trinidad</dc:creator>
      <dc:creator>Fernández González, Ana</dc:creator>
      <dc:creator>Arias Santiago, Salvador Antonio</dc:creator>
      <dc:subject>Exosomes-based therapy</dc:subject>
      <dc:subject>Immunomodulation</dc:subject>
      <dc:subject>Mesenchymal stem cell-derived exosomes</dc:subject>
      <dc:subject>Regenerative medicine</dc:subject>
      <dc:subject>Skin autoimmune diseases</dc:subject>
      <dc:subject>Skin wound healing</dc:subject>
      <dc:description>This study has been funded by the Carlos III Health Institute of Spain through the PI13/02576 and PI17/02083 projects [cofunded by European Regional Development Fund "A way to make Europe" and Andalusian Regional Government Finance (SAS PI-0458-2016)]. The work of MQ-V was supported by a predoctoral fellowship (BOE 22/10/2019) from the Spanish Ministry of Science, Innovation and Universities. This study is part of her doctoral research in the Biomedicine program at the University of Granada.</dc:description>
      <dc:description>The skin is the largest organ of the human body and its main functions include providing protection from external harmful agents, regulating body temperature, and homeostatic maintenance. Skin injuries can damage this important barrier and its functions so research focuses on approaches to accelerate wound healing and treat inflammatory skin diseases. Due to their regenerative and immunomodulatory properties, mesenchymal stromal cells (MSCs) have been reported to play a significant role in skin repair and regeneration. However, it seems that the secretome of these cells and exosomes in particular may be responsible for their functions in skin regeneration and the immunomodulation field. The present review aims to gather the available information about the role of MSC-derived exosomes for both in vitro and in vivo models of different skin conditions and to highlight the need for further research in order to overcome any limitations for clinical translation.</dc:description>
      <dc:date>2021-05-26T06:53:40Z</dc:date>
      <dc:date>2021-05-26T06:53:40Z</dc:date>
      <dc:date>2021-04-07</dc:date>
      <dc:type>journal article</dc:type>
      <dc:identifier>Quiñones-Vico MI, Sanabria-de la Torre R, Sánchez-Díaz M, Sierra-Sánchez Á, Montero-Vílchez T, Fernández-González A and Arias-Santiago S (2021) The Role of Exosomes Derived From Mesenchymal Stromal Cells in Dermatology. Front. Cell Dev. Biol. 9:647012. doi: [10.3389/fcell.2021.647012]</dc:identifier>
      <dc:identifier>http://hdl.handle.net/10481/68723</dc:identifier>
      <dc:identifier>10.3389/fcell.2021.647012</dc:identifier>
      <dc:language>eng</dc:language>
      <dc:rights>http://creativecommons.org/licenses/by/3.0/es/</dc:rights>
      <dc:rights>open access</dc:rights>
      <dc:rights>Atribución 3.0 España</dc:rights>
      <dc:publisher>Frontiers Research Foundation</dc:publisher>
   </ow:Publication>
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