Evaluation of the Analgesic Efficacy of a Bioelectronic Device in Non-Specific Chronic Low Back Pain with Neuropathic Component. A Randomized Trial Teresa, Carlos de Varela López, Alfonso Rios Álvarez, Susana Gálvez Mateos, Rafael Maire, Coralie Gracia-Villar, Santos Battino, Maurizio Quiles Morales, José Luis Bioelectronics Electromagnetic signals Chronic low back pain Neuropathic pain Quality of life Functional capacity Low energy pulsed electromagnetic signals (PEMS) therapy, in the field of bioelectronics, has been suggested as a promising analgesic therapy with special interest in treating conditions with poor response to pharmacotherapy. This study evaluated the effectiveness of PEMS therapy on the treatment of chronic low back pain patients with a neuropathic component. A group of 64 individuals with such condition was allocated to a 2-week treatment period (10 twenty-minute sessions on consecutive days) with an active PEMS therapy device or an inactive device in random order. The pain was assessed on a visual analog scale, and the functional status was assessed using the SF-12 questionnaire. The visual analog scale scores were lower after treatment than at baseline but only in the group treated with the active device. According to the DN4 score, neuropathic pain decreased in both experimental groups with respect to baseline, but this was only significant for the group treated with the active device. Similarly, an improvement in the SF-12 and Medical Outcomes Study (MOS) sleep scale components was reported. The study demonstrated that low-energy PEMS therapy was efficient in reducing pain and improving function in chronic low back pain patients with a neuropathic component. 2021-05-14T10:50:46Z 2021-05-14T10:50:46Z 2021 info:eu-repo/semantics/article de Teresa, C.; Varela-López, A.; Rios-Álvarez, S.; Gálvez, R.; Maire, C.; Gracia-Villar, S.; Battino, M.; Quiles, J.L. Evaluation of the Analgesic Efficacy of a Bioelectronic Device in Non-Specific Chronic Low Back Pain with Neuropathic Component. A Randomized Trial. J. Clin. Med. 2021, 10, 1781. https:// doi.org/10.3390/jcm10081781 http://hdl.handle.net/10481/68527 10.3390/jcm10081781 eng http://creativecommons.org/licenses/by/3.0/es/ info:eu-repo/semantics/openAccess Atribución 3.0 España MDPI