Intraocular scattering as a predictor of driving performance in older adults with cataracts Ortiz Peregrina, Sonia Ortiz Herrera, Carolina Salas Hita, Carlos Casares López, Miriam Soler Fernández, Margarita González Anera, María Del Rosario older drivers cataract intraocular scattering driving performance road safety Cataracts can limit a person's ability to perform vision-dependent tasks safely, affecting the quality of life of older people. This study examines the relationship between visual function and driving, by studying which visual parameters might be important for predicting driving performance in older drivers with and without cataracts, ascertaining whether the objective measurement of intraocular scattering should be considered in assessment procedures for older drivers. This cross-sectional study involved a total of 20 older drivers (10 patients with bilateral cataracts and 10 control subjects). All participants were examined for visual acuity, contrast sensitivity, visual discrimination capacity, and intraocular scattering. Driving performance was also tested using a driving simulator. To study the relationship between visual parameters and driving performance, a correlation analysis and regression model were used. Drivers with cataracts showed a significantly impaired (p<0.05) visual function, with an Objective Scattering Index (OSI) 3.5 times greater than the control group. Driving performance was also significantly worse (p<0.05) in drivers with cataracts, reflected by a notable deterioration in lane keeping. The correlation analysis showed significant associations between driving performance and all the visual parameters studied. Finally, the regression model revealed that the OSI was the best predictor of driving performance, accounting for 51.3% of its variance. Visual function and driving performance are markedly deteriorated when cataracts are present. Our results demonstrate that the objective scattering index (OSI) has a high predictive power when it comes to simulated driving performance in older drivers, both with and without cataracts, suggesting that scatter measurements could be important in helping better understand visual limitations in older drivers. 2020-09-22T11:01:50Z 2020-09-22T11:01:50Z 2020-01-14 info:eu-repo/semantics/article Ortiz-Peregrina S, Ortiz C, Salas C, Casares-López M, Soler M, Anera RG (2020). Intraocular scattering as a predictor of driving performance in older adults with cataracts. PLoS ONE 15 (1): e0227892. http://hdl.handle.net/10481/63505 https://doi.org/10.1371/journal.pone.0227892 eng PLOSONE; Ministry of Economy and Competitiveness (Spain); European Regional Development Fund (ERDF) (FIS2017-85058-R), and Ministry of Science, Innovation and Universities (Spain) (Grant FPU15/05571) http://creativecommons.org/licenses/by-nc-nd/3.0/es/ info:eu-repo/semantics/openAccess Atribución-NoComercial-SinDerivadas 3.0 España Feng Chen