Probiotics Dietary Supplementation for Modulating Endocrine and Fertility Microbiota Dysbiosis López Moreno, Ana Aguilera Gómez, Margarita Probiotics Doses Microbiota Endocrine Fertility Dysbiosis Ana López Moreno and Margarita Aguilera are part of the BIO-190 Research Group. They are also part of “UGR Plan Propio de Investigación 2019–2020. Human microbiota seems to play a key role in endocrine and reproductive systems. Fortunately, microbiota reproductive dysbiosis start to be treated by probiotics using typical species from genus Lactobacillus. This work presents the compiled and analysed results from the most up-to-date information from clinical trials regarding microbiota, fertility, probiotics and oral route administration, reviewing open access scientific documents. These studies analyse the clinical impact of probiotics administered on several endocrine disorders’ manifestations in women: mastitis; vaginal dysbiosis; pregnancy complication disorders; and polycystic ovary syndrome. In all cases, the clinical modulation achieved by probiotics was evaluated positively through the improvement of specific disease outcomes with the exception of the pregnancy disorders studies, where the sample sizes results were statistically insufficient. High amounts of studies were discarded because no data were provided on specific probiotic strains, doses, impact on the individual autochthon microbiota, or data regarding specific hormonal values modifications and endocrine regulation effects. However, most of the selected studies with probiotics contained no protocolised administration. Therefore, we consider that intervention studies with probiotics might allocate the focus, not only in obtaining a final outcome, but in how to personalise the administration according to the disorder to be palliated. 2020-06-10T12:38:56Z 2020-06-10T12:38:56Z 2020-03 info:eu-repo/semantics/article López-Moreno, A., & Aguilera, M. (2020). Probiotics Dietary Supplementation for Modulating Endocrine and Fertility Microbiota Dysbiosis. Nutrients, 12(3), 757. [doi:10.3390/nu12030757] http://hdl.handle.net/10481/62425 doi:10.3390/nu12030757 eng http://creativecommons.org/licenses/by/3.0/es/ info:eu-repo/semantics/openAccess Atribución 3.0 España MDPI