Patterns of Sedentary Time and Quality of Life in Women With Fibromyalgia: Cross-Sectional Study From the al-Ándalus Project Gavilán Carrera, Blanca Segura Jiménez, Víctor Acosta Manzano, Pedro Borges-Cosic, Milkana Álvarez-Gallardo, Inmaculada C. Delgado Fernández, Manuel Sedentary behavior Symptomatology Background: Sedentary time (ST) has been associated with detrimental health outcomes in fibromyalgia. Previous evidence in the general population has shown that not only is the total amount of ST harmful but the pattern of accumulation of sedentary behaviors is also relevant to health, with prolonged unbroken periods (ie, bouts) being particularly harmful. Results: A greater percentage of ST spent in all bout lengths was associated with worsened physical function, bodily pain, vitality, social function, and physical component summary (PCS) (all P<.05). In addition, a higher percentage of ST in bouts of 60 minutes or more was related to worsened physical role (P=.04). A higher frequency of bouts was negatively associated with physical function, social function, the PCS (≥30 min and ≥60 min), physical role (≥60 min), bodily pain (≥60 min), and vitality (≥20 min, ≥30 min, and ≥60 min) (all P<.05). Overall, for different domains of HRQoL, these associations were independent of MVPA for higher bout lengths. Patients with high total ST and high sedentary bout duration had significantly worsened physical function (mean difference 8.73 units, 95% CI 2.31-15.15; independent of MVPA), social function (mean difference 10.51 units, 95% CI 2.59-18.44; not independent of MVPA), and PCS (mean difference 2.71 units, 95% CI 0.36-5.06; not independent of MVPA) than those with low ST and low sedentary bout duration. Conclusions: Greater ST in prolonged periods of any length and a higher frequency of ST bouts, especially in longer bout durations, are associated with worsened HRQoL in women with fibromyalgia. These associations were generally independent of MVPA. 2020-04-20T11:53:14Z 2020-04-20T11:53:14Z 2020 journal article Gavilán-Carrera, B., Segura-Jiménez, V., Acosta-Manzano, P., Borges-Cosic, M., Álvarez-Gallardo, I. C., & Delgado-Fernández, M. (2020). Patterns of Sedentary Time and Quality of Life in Women With Fibromyalgia: Cross-Sectional Study From the al-Ándalus Project. JMIR mHealth and uHealth, 8(3), e14538. http://hdl.handle.net/10481/61374 10.2196/14538 eng http://creativecommons.org/licenses/by/3.0/es/ open access Atribución 3.0 España JMIR Publications, Inc