<rdf:RDF xmlns:rdf="http://www.openarchives.org/OAI/2.0/rdf/" xmlns:ow="http://www.ontoweb.org/ontology/1#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:ds="http://dspace.org/ds/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:doc="http://www.lyncode.com/xoai" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/rdf/ http://www.openarchives.org/OAI/2.0/rdf.xsd">
   <ow:Publication rdf:about="oai:digibug.ugr.es:10481/60824">
      <dc:title>Relationships Between Chemical Structure and Antioxidant Activity of Isolated Phytocompounds from Lemon Verbena</dc:title>
      <dc:creator>Sánchez Marzo, Noelia</dc:creator>
      <dc:creator>Lozano Sánchez, Jesús</dc:creator>
      <dc:creator>Cádiz Gurrea, María de la Luz</dc:creator>
      <dc:creator>Herranz-López, María</dc:creator>
      <dc:creator>Micol Molina, Vicente</dc:creator>
      <dc:creator>Segura Carretero, Antonio</dc:creator>
      <dc:subject>Lemon verbena</dc:subject>
      <dc:subject>RP-HPLC-ESI-TOF-MS</dc:subject>
      <dc:subject>Semi-preparative chromatography</dc:subject>
      <dc:subject>Isolation</dc:subject>
      <dc:subject>Antioxidant</dc:subject>
      <dc:subject>Structure-activity relationship</dc:subject>
      <dc:description>The following are available online at https://www.mdpi.com/2076-3921/8/8/324/s1, Figure S1. UV chromatograms at 280 nm and MS spectra for (A) peak 5 and (B) peak 28; Figure S2. Base peak chromatograms of the collected fractions from a commercial lemon verbena extract (PLX®10) and MS spectra of their major compound, including the peak numbers of Table 1; Table S1. In vitro antioxidant activity by FRAP, TEAC and ORAC assays for the commercial lemon verbena extract (PLX®10) and its collected fractions, expressed as the mean of three independent replicates ± the standard deviation.</dc:description>
      <dc:description>Over the last few years, people have been concerned about the narrow relationship between nutrition and health leading to an increasing demand of nutraceutical products and functional food. Lemon verbena (Lippia citriodora Kunth) has been traditionally used for respiratory, digestive, and muscular diseases, showing effects that are promoted by the antioxidant activity of its phytoconstituents. The antioxidant power of several lemon verbena extracts has been tested but its isolated compounds activity has not been described. The aim of the present work was to isolate phytochemicals from a commercial lemon verbena extract through a semi-preparative high-performance liquid chromatography approach for further evaluation of its individual antioxidant activity using three different methods. The structure-antioxidant activity relationships revealed the influence of substitutions in the strong antioxidant power exerted by glycosylated phenylpropanoids, in contrast to the low antioxidant capacity showed by iridoids. Development of enriched extracts in these compounds could lead to greater antioxidant effects and improved functional ingredients to prevent chronic diseases.</dc:description>
      <dc:date>2020-03-30T12:29:51Z</dc:date>
      <dc:date>2020-03-30T12:29:51Z</dc:date>
      <dc:date>2019-08-20</dc:date>
      <dc:type>info:eu-repo/semantics/article</dc:type>
      <dc:identifier>Sánchez-Marzo, N.; Lozano-Sánchez, J.; Cádiz-Gurrea, M.L.; Herranz-López, M.; Micol, V.; Segura-Carretero, A. Relationships Between Chemical Structure and Antioxidant Activity of Isolated Phytocompounds from Lemon Verbena. Antioxidants 2019, 8, 324 [doi:10.3390/antiox8080324]</dc:identifier>
      <dc:identifier>http://hdl.handle.net/10481/60824</dc:identifier>
      <dc:identifier>10.3390/antiox8080324</dc:identifier>
      <dc:language>eng</dc:language>
      <dc:rights>http://creativecommons.org/licenses/by/3.0/es/</dc:rights>
      <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
      <dc:rights>Atribución 3.0 España</dc:rights>
      <dc:publisher>MDPI</dc:publisher>
   </ow:Publication>
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