X chromosome genetic data in a Spanish children cohort, dataset description and analysis pipeline Anguita-Ruiz, Augusto Plaza Díaz, Julio Ruiz Ojeda, Francisco Javier Rupérez Cano, Azahara Iris Leis, Rosaura Bueno, Gloria Gil-Campos, Mercedes Vázquez Cobela, Rocío Cañete, Ramón Moreno, Luis A. Gil Hernández, Ángel Aguilera García, Concepción María X chromosome genetic variation has been proposed as a potential source of missing heritability for many complex diseases, including obesity. Currently, there is a lack of public available genetic datasets incorporating X chromosome genotype data. Although several X chromosome-specific statistics have been developed, there is also a lack of readily available implementations for routine analysis. Here, we aimed: (1) to make public and describe a dataset incorporating phenotype and X chromosome genotype data from a cohort of 915 normal-weight, overweight and obese children, and (2) to deeply describe a whole implementation of the special X chromosome analytic process in genetics. Datasets and pipelines like this are crucial to get familiar with the steps in which X chromosome requires special attention and may raise awareness of the importance of this genomic region. 2020-03-10T10:32:48Z 2020-03-10T10:32:48Z 2019-07-22 info:eu-repo/semantics/article Anguita-Ruiz, A., Plaza-Diaz, J., Ruiz-Ojeda, F. J., Rupérez, A. I., Leis, R., Bueno, G., ... & Gil, Á. (2019). X chromosome genetic data in a Spanish children cohort, dataset description and analysis pipeline. Scientific data, 6(1), 1-10. http://hdl.handle.net/10481/60180 10.1038/s41597-019-0109-3 eng http://creativecommons.org/licenses/by/3.0/es/ info:eu-repo/semantics/openAccess Atribución 3.0 España Springer Nature