Speed of Retinal Vascularization in Retinopathy of Prematurity: Risk and Protective Factors Solans Pérez de Larraya, Ana María Ortega-Molina, JM Uberos Fernández, José González Ramírez, Amanda Rocío García Serrano, José Luis Objective.The objective was to study the risk and protective factors involved in retinal vascular development of preterminfantswith retinopathy of prematurity. Methods. Between 2000 and 2017, 185 preterm infants were included in the protocol for retinopathy of prematurity. Risk factors associated with speed of retinal vascularization <0.5 disc diameter/week were studied in each of them. Results.The statistically significant variables related to retinal vascular development <0.5 DD/w were intubation days, degree 3 of bronchopulmonary dysplasia, weight gain at 4-6 weeks, avascular temporal area, gestational age, number of transfusions, sepsis, number of risk factors, apnea at birth, presence of ductus arteriosus, and days of continuous positive airway pressure therapy. After the multivariate logistic regression analysis, only three variables were found to be significant: intubation days (p=0.005), degree 3 of bronchopulmonary dysplasia (p=0.022), and weight gain at 4–6 weeks (p=0.031). Conclusion. In retinopathy of prematurity, degree 3 of bronchopulmonary dysplasia and intubation days cause delayed retinal vascular development,whereas greater postnatal weight gain favors an appropriate rate of retinal vascularization. 2020-02-20T11:30:59Z 2020-02-20T11:30:59Z 2019 info:eu-repo/semantics/article Solans Pérez de Larraya, A. M., Ortega Molina, J. M., Uberos Fernández, J., González Ramírez, A. R., & García Serrano, J. L. (2019). Speed of Retinal Vascularization in Retinopathy of Prematurity: Risk and Protective Factors. BioMed research international, 2019. http://hdl.handle.net/10481/59788 10.1155/2019/2721578 eng http://creativecommons.org/licenses/by/3.0/es/ info:eu-repo/semantics/openAccess Atribución 3.0 España Hindawi