Linking of psoriasis with osteopenia and osteoporosis: A cross‑sectional study Blasco Morente, Gonzalo Martínez López, Antonio Girón Prieto, María Sierra Arrabal Polo, Miguel Ángel Luque Valenzuela, María Luna Del Castillo, Juan De Dios Tercedor Sánchez, Jesús Arias Santiago, Salvador Antonio Body mass index Bone mineral density Osteopenia Osteoporosis Psoriasis Vitamin D Psoriasis is a multisystem disease which has been related to vitamin‑D deficiency through chronic inflammation. This psoriasis‑related inflammatory state and vitamin‑D deficiency may induce bone mineral density loss. The purpose of this study is to assess the relationship of psoriasis with bone mineral density, by comparing psoriatic patients with healthy controls and patients with osteopenia/osteoporosis. Psoriatic patients showed worse hip and lumbar spine bone mineral density levels than healthy controls (P = 0.001) and better levels than osteoporotic patients (P < 0.001). Multivariate analysis demonstrated a negative association of age and a positive association of body mass index in hip bone mineral density in psoriatic patients. Bone mineral density levels in psoriatic patients are situated halfway between healthy controls and patients with osteopenia/osteoporosis. In addition, the higher body mass index in patients with psoriasis appears to confer a protective effect against further development of lower bone mineral density. 2020-02-10T09:57:50Z 2020-02-10T09:57:50Z 2019 journal article Martinez-Lopez A, Blasco-Morente G, Giron-Prieto MS, Arrabal-Polo MA, Luque-Valenzuela M, Luna-Del Castillo JD, et al. Linking of psoriasis with osteopenia and osteoporosis: A cross-sectional study. Indian J Dermatol Venereol Leprol 2019;85:153-9. http://hdl.handle.net/10481/59533 eng http://creativecommons.org/licenses/by-nc-sa/3.0/es/ open access Atribución-NoComercial-CompartirIgual 3.0 España Wolters Kluwer Health, Inc.