<rdf:RDF xmlns:rdf="http://www.openarchives.org/OAI/2.0/rdf/" xmlns:ow="http://www.ontoweb.org/ontology/1#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:ds="http://dspace.org/ds/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:doc="http://www.lyncode.com/xoai" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/rdf/ http://www.openarchives.org/OAI/2.0/rdf.xsd">
   <ow:Publication rdf:about="oai:digibug.ugr.es:10481/58680">
      <dc:title>Water Extract of Cryphaea heteromalla (Hedw.) D. Mohr Bryophyte as a Natural Powerful Source of Biologically Active Compounds</dc:title>
      <dc:creator>Provenzano, Fiorenza</dc:creator>
      <dc:creator>Lozano Sánchez, Jesús</dc:creator>
      <dc:creator>Borras Linares, María Isabel</dc:creator>
      <dc:creator>Segura Carretero, Antonio</dc:creator>
      <dc:subject>Bryophytes</dc:subject>
      <dc:subject>Cryphaea heteromalla</dc:subject>
      <dc:subject>Extract HPLC-ESI-TOF-MS analysis</dc:subject>
      <dc:subject>Oxidative stress evaluation</dc:subject>
      <dc:description>Bryophytes comprise of the mosses, liverworts, and hornworts. Cryphaea heteromalla,&#xd;
(Hedw.) D. Mohr, is a non-vascular lower plant belonging to mosses group. To the date, the most&#xd;
chemically characterized species belong to the liverworts, while only 3.2% and 8.8% of the species&#xd;
belonging to the mosses and hornworts, respectively, have been investigated. In this work, we present&#xd;
Folin–Ciocalteu and oxygen radical absorbance capacity (ORAC) data related to crude extracts of C.&#xd;
heteromalla obtained by three di erent extraction solvents: pure water (WT), methanol:water (80:20&#xd;
v/v) (MET), and ethanol:water (80:20 v/v) (ETH). The water extract proved to be the best solvent&#xd;
showing the highest content of biophenols and the highest ORAC value. The C. heteromalla-WT&#xd;
extract was investigated by HPLC-TOF/MS (High Performance Liquid Chromatography-Time of&#xd;
Flight/Mass Spectrometry) allowing for the detection of 14 compounds, five of which were phenolic&#xd;
compounds, derivatives of benzoic, caffeic, and coumaric acids. Moreover, the C. heteromalla WT&#xd;
extract showed a protective effect against reactive oxygen species (ROS) generation induced by&#xd;
tert-butyl hydroperoxide (TBH) on the murine NIH-3T3 fibroblast cell line.</dc:description>
      <dc:date>2020-01-13T09:42:04Z</dc:date>
      <dc:date>2020-01-13T09:42:04Z</dc:date>
      <dc:date>2019-11-07</dc:date>
      <dc:type>journal article</dc:type>
      <dc:identifier>Provenzano, F., Sánchez, J. L., Rao, E., Santonocito, R., Ditta, L. A., Borrás Linares, I., ... &amp; Segura-Carretero, A. (2019). Water Extract of Cryphaea heteromalla (Hedw.) D. Mohr Bryophyte as a Natural Powerful Source of Biologically Active Compounds. International journal of molecular sciences, 20(22), 5560.</dc:identifier>
      <dc:identifier>http://hdl.handle.net/10481/58680</dc:identifier>
      <dc:identifier>10.3390/ijms20225560</dc:identifier>
      <dc:language>eng</dc:language>
      <dc:rights>http://creativecommons.org/licenses/by/3.0/es/</dc:rights>
      <dc:rights>open access</dc:rights>
      <dc:rights>Atribución 3.0 España</dc:rights>
      <dc:publisher>MDPI</dc:publisher>
   </ow:Publication>
</rdf:RDF>