<rdf:RDF xmlns:rdf="http://www.openarchives.org/OAI/2.0/rdf/" xmlns:ow="http://www.ontoweb.org/ontology/1#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:ds="http://dspace.org/ds/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:doc="http://www.lyncode.com/xoai" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/rdf/ http://www.openarchives.org/OAI/2.0/rdf.xsd">
   <ow:Publication rdf:about="oai:digibug.ugr.es:10481/58606">
      <dc:title>Associations between Dietary Polyphenols and Type 2 Diabetes in a Cross-Sectional Analysis of the PREDIMED-Plus Trial: Role of Body Mass Index and Sex</dc:title>
      <dc:creator>Tresserra Rimbau, Anna</dc:creator>
      <dc:creator>García Molina, Laura</dc:creator>
      <dc:subject>Hydroxybenzoic acids</dc:subject>
      <dc:subject>Hydroxycinnamic acids</dc:subject>
      <dc:subject>Phenolic acids</dc:subject>
      <dc:subject>Diet</dc:subject>
      <dc:subject>Obesity</dc:subject>
      <dc:subject>Flavonoids</dc:subject>
      <dc:subject>Catechins</dc:subject>
      <dc:description>Overweight and obesity are important risk factors for type 2 diabetes (T2D). Moving towards&#xd;
healthier diets, namely, diets rich in bioactive compounds, could decrease the odds of suffering&#xd;
T2D. However, those individuals with high body mass index (BMI) may have altered absorption&#xd;
or metabolism of some nutrients and dietary components, including polyphenols. Therefore, we&#xd;
aimed to assess whether high intakes of some classes of polyphenols are associated with T2D in a&#xd;
population with metabolic syndrome and how these associations depend on BMI and sex. This baseline&#xd;
cross-sectional analysis includes 6633 participants from the PREDIMED-Plus trial. Polyphenol intakes&#xd;
were calculated from food frequency questionnaires (FFQ). Cox regression models with constant&#xd;
time at risk and robust variance estimators were used to estimate the prevalence ratios (PRs) for polyphenol intake and T2D prevalence using the lowest quartile as the reference group. Analyses&#xd;
were stratified by sex and BMI groups (overweight and obese) to evaluate potential effect modification.&#xd;
Catechins, proanthocyanidins, hydroxybenzoic acids, and lignans were inversely associated with T2D.&#xd;
Hydroxycinnamic acids were directly related in men. These associations were different depending on&#xd;
sex and BMI, that is, women and overweight obtained stronger inverse associations.</dc:description>
      <dc:date>2020-01-09T13:47:43Z</dc:date>
      <dc:date>2020-01-09T13:47:43Z</dc:date>
      <dc:date>2019-11-08</dc:date>
      <dc:type>info:eu-repo/semantics/article</dc:type>
      <dc:identifier>Tresserra-Rimbau, A., Castro-Barquero, S., Vitelli-Storelli, F., Becerra-Tomas, N., Vázquez-Ruiz, Z., Díaz-López, A., ... &amp; Alonso-Gómez, Á. M. (2019). Associations between Dietary Polyphenols and Type 2 Diabetes in a Cross-Sectional Analysis of the PREDIMED-Plus Trial: Role of Body Mass Index and Sex. Antioxidants, 8(11), 537.</dc:identifier>
      <dc:identifier>http://hdl.handle.net/10481/58606</dc:identifier>
      <dc:identifier>10.3390/antiox8110537</dc:identifier>
      <dc:language>eng</dc:language>
      <dc:rights>http://creativecommons.org/licenses/by/3.0/es/</dc:rights>
      <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
      <dc:rights>Atribución 3.0 España</dc:rights>
      <dc:publisher>MDPI</dc:publisher>
   </ow:Publication>
</rdf:RDF>