Effect of daily consumption of extra virgin olive oil on the lipid profile and microbiota of HIV-infected patients over 50 years of age Olalla, Julián Chueca-Porcuna, Natalia Salazar, Adolfo de Plaza Díaz, Julio García, Federico Aging Cholesterol Extra-virgin olive oil Microbiota Extra virgin olive oil (EVOO) has shown beneficial effects on the lipid profile and inflammatory parameters in general population. Our goal is to analyze these changes together with those of intestinal microbiota in human immunodeficiency virus (HIV)-infected patients over 50 years of age. Total cholesterol decreased significantly (5 mg/dL), and a nonsignificant decrease in low-density lipoprotein cholesterol (12 mg/dL), triglycerides (21 mg/dL), and CRP (1.25 mg/dL) was observed. There was a significant increase in alpha diversity after the intervention in men and a decrease in proinflammatory genera such as Dethiosulfovibrionaceae was observed. Differences were also observed in the microbiota of men and women and according to the type of antiretroviral treatment. Sustained consumption of 50g of EVOO in elderly HIV-infected patients might be associated with an improvement in lipid profile and alfa diversity of intestinal microbiota. 2019-12-13T10:00:41Z 2019-12-13T10:00:41Z 2019-09-19 info:eu-repo/semantics/article Olalla, J., de Lomas, J. M. G., Chueca, N., Pérez-Stachowski, X., De Salazar, A., Del Arco, A., ... & Fernández-Sánchez, F. (2019). Effect of daily consumption of extra virgin olive oil on the lipid profile and microbiota of HIV-infected patients over 50 years of age. Medicine, 98(42). http://hdl.handle.net/10481/58286 10.1097/MD.0000000000017528 eng http://creativecommons.org/licenses/by/3.0/es/ info:eu-repo/semantics/openAccess Atribución 3.0 España Wolters Kluwer Health, Inc.