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   <ow:Publication rdf:about="oai:digibug.ugr.es:10481/58095">
      <dc:title>Newborn infants' hair cortisol levels reflect chronic maternal stress during pregnancy</dc:title>
      <dc:creator>Romero González, Borja</dc:creator>
      <dc:creator>Caparrós González, Rafael Arcángel</dc:creator>
      <dc:creator>González Pérez, Raquel</dc:creator>
      <dc:creator>Delgado Puertas, Pilar</dc:creator>
      <dc:creator>Peralta Ramírez, María Isabel</dc:creator>
      <dc:description>Cortisol obtained from hair samples represents a retrospective biomarker of chronic stress&#xd;
experienced by the subject in previous months. Although hair cortisol levels have been used to&#xd;
study the relationship between maternal and neonatal stress levels in primates, this has not yet&#xd;
been performed in humans using a longitudinal design and focusing specifically on this association.&#xd;
Therefore, the objective of this study was to determine whether a relationship existed&#xd;
between maternal psychological stress and hair cortisol levels during pregnancy and postpartum,&#xd;
and neonatal hair cortisol levels. The sample consisted of 80 pregnant women and their&#xd;
80 newborn infants. We conducted a longitudinal assessment of hair cortisol levels, psychological&#xd;
stress, anxiety, and depression in the three trimesters of pregnancy and postpartum. After&#xd;
childbirth, neonatal hair cortisol levels were also measured. We found that maternal hair cortisol&#xd;
levels in the first trimester negatively predicted neonatal hair cortisol levels. Perceived stress in&#xd;
the third trimester of pregnancy also predicted lower neonatal cortisol, whereas pregnancyspecific&#xd;
stress in the same trimester had a positive relation with neonatal cortisol. Cortisol is&#xd;
essential for embryonic and fetal development; consequently, if fetal synthesis of cortisol is&#xd;
affected by high maternal cortisol levels, such development could be impaired.</dc:description>
      <dc:date>2019-11-27T12:46:58Z</dc:date>
      <dc:date>2019-11-27T12:46:58Z</dc:date>
      <dc:date>2018-07-06</dc:date>
      <dc:type>journal article</dc:type>
      <dc:identifier>Romero-Gonzalez B, Caparros-Gonzalez RA, Gonzalez-Perez R, Delgado-Puertas P, Peralta- Ramirez MI (2018) Newborn infants' hair cortisol levels reflect chronic maternal stress during pregnancy. PLoS ONE 13(7): e0200279.</dc:identifier>
      <dc:identifier>http://hdl.handle.net/10481/58095</dc:identifier>
      <dc:identifier>10.1371/journal.pone.0200279</dc:identifier>
      <dc:language>eng</dc:language>
      <dc:rights>http://creativecommons.org/licenses/by/3.0/es/</dc:rights>
      <dc:rights>open access</dc:rights>
      <dc:rights>Atribución 3.0 España</dc:rights>
      <dc:publisher>PLOS</dc:publisher>
   </ow:Publication>
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