The effects of oral smokeless tobacco administration on endurance performance Zandonai, Thomas Exercise endurance Maximal aerobic power Smokeless tobacco Tissue oxygenation Smokeless tobacco is widely used by athletes to enhance performance. Nicotine is a central nervous system stimulant and acts on cardiocirculatory and metabolic systems, involving tissue blood flow and circulatory vasoreactivity. The aim of this study was to investigate the effects of the oral smokeless tobacco (Swedish snus (SS)) on the perception of fatigue and time to exhaustion (TTE) during moderate-intensity aerobic exercise. Comparing SS with SP tests, significant differences (p < 0.05) were found in the values of cerebral (~3%) and muscular tissues oxygenation (~4%) in the first 30 min of exercise. The RPE values were not significantly different between the 2 conditions (SS vs. SP). No significant difference was found in TTE (SS: 54.25 ± 21.84 min; SP: 50.01 ± 17.03 min). This study showed that muscular and cerebral oxygenation increased significantly with snus administration during an endurance exercise until exhaustion, but this did not affect fatigue perception and TTE. The results showed that snus could not be considered an ergogenic substance in non-tobacco users. 2019-10-31T09:19:21Z 2019-10-31T09:19:21Z 2016-12-28 info:eu-repo/semantics/article Zandonai, T., Tam, E., Bruseghini, P., Pizzolato, F., Franceschi, L., Baraldo, M., ... & Chiamulera, C. (2018). The effects of oral smokeless tobacco administration on endurance performance. Journal of sport and health science, 7(4), 465-472. http://hdl.handle.net/10481/57634 10.1016/j.jshs.2016.12.006 eng http://creativecommons.org/licenses/by-nc-nd/3.0/es/ info:eu-repo/semantics/openAccess Atribución-NoComercial-SinDerivadas 3.0 España Elsevier BV