<rdf:RDF xmlns:rdf="http://www.openarchives.org/OAI/2.0/rdf/" xmlns:ow="http://www.ontoweb.org/ontology/1#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:ds="http://dspace.org/ds/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:doc="http://www.lyncode.com/xoai" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/rdf/ http://www.openarchives.org/OAI/2.0/rdf.xsd">
   <ow:Publication rdf:about="oai:digibug.ugr.es:10481/57471">
      <dc:title>InterdisciplinaryWeight Loss and Lifestyle Intervention for Obstructive Sleep Apnoea in Adults: Rationale, Design and Methodology of the INTERAPNEA Study</dc:title>
      <dc:creator>Carneiro Barrera, Almudena</dc:creator>
      <dc:creator>Amaro Gahete, Francisco José</dc:creator>
      <dc:creator>Díaz Román, Amparo</dc:creator>
      <dc:creator>Guillén Riquelme, Alejandro</dc:creator>
      <dc:creator>Jurado Fasoli, Lucas</dc:creator>
      <dc:creator>Sáez Roca, Germán</dc:creator>
      <dc:creator>Martín Carrasco, Carlos</dc:creator>
      <dc:creator>Ruiz Ruiz, Jonatan</dc:creator>
      <dc:creator>Buela Casal, Gualberto</dc:creator>
      <dc:subject>Obstructive sleep apnoea</dc:subject>
      <dc:subject>Apnoea-hypopnoea index</dc:subject>
      <dc:subject>Obesity</dc:subject>
      <dc:subject>Weight loss</dc:subject>
      <dc:subject>Interdisciplinary lifestyle intervention</dc:subject>
      <dc:subject>Nutrition</dc:subject>
      <dc:subject>Sleep hygiene</dc:subject>
      <dc:description>Obesity is a major risk factor for obstructive sleep apnoea (OSA), the most common&#xd;
sleep-disordered breathing related to neurocognitive and metabolic syndromes, type II diabetes, and&#xd;
cardiovascular diseases. Although strongly recommended for this condition, there are no studies on&#xd;
the e ectiveness of an interdisciplinary weight loss and lifestyle intervention including nutrition,&#xd;
exercise, sleep hygiene, and smoking and alcohol cessation. INTERAPNEA is a randomised controlled&#xd;
trial with a two-arm parallel design aimed at determining the e ects of an interdisciplinary tailored&#xd;
weight loss and lifestyle intervention on OSA outcomes. The study will include 84 males aged&#xd;
18–65 with a body mass index of  25 kg/m2 and severe to moderate OSA randomly assigned to&#xd;
usual care (i.e., continuous positive airway pressure), or interdisciplinary weight loss and lifestyle&#xd;
intervention combined with usual care. Outcomes will be measured at baseline, intervention end-point,&#xd;
and six-month post-intervention, including apnoea-hypopnoea index (primary outcome), other&#xd;
neurophysical and cardiorespiratory polysomnographic outcomes, sleep quality, daily functioning&#xd;
and mood, body weight and composition, physical fitness, blood biomarkers, health-related quality of&#xd;
life, and cost-e ectiveness. INTERAPNEA may serve to establish a cost-e ective treatment not only&#xd;
for the improvement of OSA and its vast and severe comorbidities, but also for a potential remission&#xd;
of this condition.</dc:description>
      <dc:date>2019-10-23T09:38:12Z</dc:date>
      <dc:date>2019-10-23T09:38:12Z</dc:date>
      <dc:date>2019-09-15</dc:date>
      <dc:type>journal article</dc:type>
      <dc:identifier>Carneiro-Barrera, A., Amaro-Gahete, F. J., Díaz-Román, A., Guillén-Riquelme, A., Jurado-Fasoli, L., Sáez-Roca, G., ... &amp; Buela-Casal, G. (2019). Interdisciplinary Weight Loss and Lifestyle Intervention for Obstructive Sleep Apnoea in Adults: Rationale, Design and Methodology of the INTERAPNEA Study. Nutrients, 11(9), 2227.</dc:identifier>
      <dc:identifier>http://hdl.handle.net/10481/57471</dc:identifier>
      <dc:identifier>10.3390/nu11092227</dc:identifier>
      <dc:language>eng</dc:language>
      <dc:rights>http://creativecommons.org/licenses/by/3.0/es/</dc:rights>
      <dc:rights>open access</dc:rights>
      <dc:rights>Atribución 3.0 España</dc:rights>
      <dc:publisher>MDPI</dc:publisher>
   </ow:Publication>
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