Catalytically Active Imine-based Covalent Organic Frameworks for Detoxification of Nerve Agent Simulants in Aqueous Media Royuela, Sergio Gil-San Millán, Rodrigo Mancheño, María J. Ramos, M. Mar Segura, Jose L. Rodríguez Navarro, Jorge Andrés Zamora, Félix covalent organic frameworks Catalysis chemical warfare agents detoxification A series of imine-based covalent organic frameworks decorated in their cavities with di erent alkynyl, pyrrolidine, and N-methylpyrrolidine functional groups have been synthetized. These materials exhibit catalytic activity in aqueous media for the hydrolytic detoxification of nerve agents, as exemplified with nerve gas simulant diisopropylfluorophosphate (DIFP). These preliminary results suggest imine-based covalent organic frameworks (COFs) as promising materials for detoxification of highly toxic molecules. 2019-10-15T10:31:07Z 2019-10-15T10:31:07Z 2019-06-19 journal article Royuela, S., Millán, G. S., Mancheño, M. J., Ramos, M., Segura, J. L., Navarro, J. A., & Zamora, F. (2019). Catalytically Active Imine-based Covalent Organic Frameworks for Detoxification of Nerve Agent Simulants in Aqueous Media. Materials, 12(12), 1974. http://hdl.handle.net/10481/57357 10.3390/ma12121974 eng http://creativecommons.org/licenses/by/3.0/es/ open access Atribución 3.0 España Materials