Cultural Adaptation and Validation of the Inflammatory Bowel Disease Disability Index in a Spanish Population and Its Association with Sociodemographic and Clinical Factors López Cortés, Rafael Herrero-Hahn, Raquel De la Rosa-Eduardo, Rosanna Montoya-Juárez, Rafael García Caro, María Paz Marín Fernández, Blanca Hueso-Montoro, César Inflammatory bowel disease Disability Quality of life Inflammatory bowel diseases generate disability. We aimed to adapt and validate the Inflammatory Bowel Disease Disability Index in a Spanish population and to analyze the sociodemographic and clinical factors associated with disability in patients with Crohn’s disease and ulcerative colitis. Cultural adaptation and validation of psychometric properties in the index were done, along with an observational, cross-sectional, and analytical approach to determine associations with sociodemographic and clinical factors. Sociodemographic data, quality of life (using the Inflammatory Bowel Disease Questionnaire-32), and indicators of disease activity were collected, among others. A total of 170 subjects participated. The index showed high internal consistency, with a Cronbach’s alpha of 0.869 and concurrent validity with the Inflammatory Bowel Disease Questionnaire-32 (r = 0.723, p < 0.001). The average score of the index was -3.91. Greater degrees of disability were found in women (mean = -6.77) than in men (mean = -1.25) (p = 0.018), in patients with Crohn’s disease (mean = -5.94) rather than those with ulcerative colitis (mean = -0.94) (p = 0.028), and in patients in the moderately active disease phase (mean = -20.94) rather than those in the mildly active disease phase (mean = -2.65) and/or those in remission (mean = -1.40) (p < 0.001). The Disability Index is a valid tool for the Spanish population and is associated with sex, type of illness, and disease activity. It is a useful index in evaluating and monitoring disability in patients with inflammatory bowel disease. 2019-02-26T12:18:33Z 2019-02-26T12:18:33Z 2019-02-21 journal article López Cortés, Rafael; Herrero-Hahn, Raquel; De la Rosa-Eduardo, Rosanna; Montoya-Juárez, Rafael; García-Caro, María Paz; Marín Fernández, Blanca; Hueso-Montoro, César. Cultural Adaptation and Validation of the Inflammatory Bowel Disease Disability Index in a Spanish Population and Its Association with Sociodemographic and Clinical Factors. Int. J. Environ. Res. Public Health 2019, 16, 635. [ doi:10.3390/ijerph16040635] 1660-4601 1661-7827 http://hdl.handle.net/10481/54847 10.3390/ijerph16040635 eng http://creativecommons.org/licenses/by/3.0/es/ open access Atribución 3.0 España MDPI