A zinc-doped endodontic cement facilitates functional mineralization and stress dissipation at the dentin surface. Pérez-Álvarez, Mayra C. Osorio Ruiz, María Estrella Lynch, Christopher D. Toledano Osorio, Manuel Toledano Pérez, Manuel Osorio Ruiz, Raquel Dentin Fracture Hydroxyapatite Remineralization Viscoelastic Zinc Objective: The purpose of this study was to evaluate nanohardness and viscoelastic behavior of dentin surfaces treated with two canal sealer cements for dentin remineralization. Material and Methods: Dentin surfaces were subjected to: i) 37% phosphoric acid (PA) or ii) 0.5 M ethylenediaminetetraacetic acid (EDTA) conditioning prior to the application of two experimental hydroxyapatite-based cements, containing sodium hydroxide (calcypatite) or zinc oxide (oxipatite), respectively. Samples were stored in simulated body fluid during 24 h or 21 d. The intertubular and peritubular dentin were evaluated using a nanoindenter to assess nanohardness (Hi). The load/displacement responses were used for the nano-dynamic mechanical analysis to estimate complex modulus (E*) and tan delta (δ). The modulus mapping was obtained by imposing a quasistatic force setpoint to which a sinusoidal force was superimposed. AFM imaging and FESEM analysis were performed. Results: After 21 d of storage, dentin surfaces treated with EDTA+calcypatite, PA+calcypatite and EDTA+oxipatite showed viscoelastic discrepancies between peritubular and intertubular dentin, meaning a risk for cracking and breakdown of the surface. At both 24 h and 21 d, tan δ values at intertubular dentin treated with the four treatments performed similar. At 21 d time point, intertubular dentin treated with PA+oxipatite achieved the highest complex modulus and nanohardness, i.e., highest resistance to deformation and functional mineralization, among groups. Conclusions: Intertubular and peritubular dentin treated with PA+oxipatite showed similar values of tan δ after 21 d of storage. This produced a favorable dissipation of energy with minimal energy concentration, preserving the structural integrity at the dentin surface. 2018-11-08T11:49:05Z 2018-11-08T11:49:05Z 2018-11 info:eu-repo/semantics/article Toledano-Osorio M. A zinc-doped endodontic cement facilitates functional mineralization and stress dissipation at the dentin surface. Med Oral Patol Oral Cir Bucal. 2018 Nov 1;23(6):e646-e655. [http://hdl.handle.net/10481/53639] http://hdl.handle.net/10481/53639 10.4317/medoral.22751 eng http://creativecommons.org/licenses/by-nc-nd/3.0/es/ info:eu-repo/semantics/openAccess Atribución-NoComercial-SinDerivadas 3.0 España