McCLEC, a robust and stable enzymatic based microreactor platform Conejero-Muriel, Mayte Rodríguez-Ruiz, Isaac Martínez-Ruiz, Sergio Llobera, Andreu Gavira Gallardo, José Antonio Microfluidic Crystallization Device McCLEC Enzyme Assay A microfluidic chip for cross-linked enzyme crystals (McCLEC) is presented and demonstrated to be a stable, reusable and robust biocatalyst-based device with very promising biotechnological applications. The cost-effective microfluidic platform allows in situ crystallization, cross-linking and enzymatic reaction assays on a single device. A large number of enzymatic reuses of the McCLEC platform were achieved and a comparative analysis is shown illustrating the efficiency of the process and its storage stability for more than one year. 2017-09-22T09:37:07Z 2017-09-22T09:37:07Z 2015-08-20 journal article Conejero-Muriel, M.; et al. McCLEC, a robust and stable enzymatic based microreactor platform. Lab on a Chip, 15: 4083-4089 (2015). [http://hdl.handle.net/10481/47518] 1473-0197 http://hdl.handle.net/10481/47518 10.1039/c5lc00776c eng http://creativecommons.org/licenses/by-nc-nd/3.0/ open access Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License Royal Society of Chemistry