Bayesian variable selection in cost-effectiveness analysis Negrín, Miguel A. Vázquez-Polo, Francisco J. Martel-Escobar, María del Carmen Moreno, Elías Girón, Francisco J. Variable selection Bayesian analysis Cost-effectiveness BIC Intrinsic Bayes factor Fractional Bayes Factor Subgroup analysis Linear regression models are often used to represent the cost and effectiveness of medical treatment. The covariates used may include sociodemographic variables, such as age, gender or race; clinical variables, such as initial health status, years of treatment or the existence of concomitant illnesses; and a binary variable indicating the treatment received. However, most studies estimate only one model, which usually includes all the covariates. This procedure ignores the question of uncertainty in model selection. In this paper, we examine four alternative Bayesian variable selection methods that have been proposed. In this analysis, we estimate the inclusion probability of each covariate in the real model conditional on the data. Variable selection can be useful for estimating incremental effectiveness and incremental cost, through Bayesian model averaging, as well as for subgroup analysis. 2014-06-17T12:45:50Z 2014-06-17T12:45:50Z 2010 journal article Negrín, M.A.; et al. Bayesian variable selection in cost-effectiveness analysis. International Journal of Environmental Research and Public Health, 7: 1577-1596 (2010). [http://hdl.handle.net/10481/32287] 1660-4601 http://hdl.handle.net/10481/32287 10.3390/ijerph7041577 eng open access MDPI