Validity of resting energy expenditure predictive equations before and after an energy-restricted diet intervention in obese women Ruiz Ruiz, Jonatan Ortega Porcel, Francisco Bartolomé Rodríguez, G. Alkorta, P. Labayen, Idoia Energy metabolism Obesity Morbid obesity Weight loss Body weight Indirect calorimetry Diet Body mass index Background We investigated the validity of REE predictive equations before and after 12-week energy-restricted diet intervention in Spanish obese (30 kg/m2>BMI<40 kg/m2) women. Methods We measured REE (indirect calorimetry), body weight, height, and fat mass (FM) and fat free mass (FFM, dual X-ray absorptiometry) in 86 obese Caucasian premenopausal women aged 36.7±7.2 y, before and after (n = 78 women) the intervention. We investigated the accuracy of ten REE predictive equations using weight, height, age, FFM and FM. Results At baseline, the most accurate equation was the Mifflin et al. (Am J Clin Nutr 1990; 51: 241–247) when using weight (bias:−0.2%, P = 0.982), 74% of accurate predictions. This level of accuracy was not reached after the diet intervention (24% accurate prediction). After the intervention, the lowest bias was found with the Owen et al. (Am J Clin Nutr 1986; 44: 1–19) equation when using weight (bias:−1.7%, P = 0.044), 81% accurate prediction, yet it provided 53% accurate predictions at baseline. Conclusions There is a wide variation in the accuracy of REE predictive equations before and after weight loss in non-morbid obese women. The results acquire especial relevance in the context of the challenging weight regain phenomenon for the overweight/obese population. 2013-10-31T10:47:46Z 2013-10-31T10:47:46Z 2011 journal article Ruiz, J.R.; et al. Validity of resting energy expenditure predictive equations before and after an energy-restricted diet intervention in obese women. Plos One, 6(9): e23759 (2011). [http://hdl.handle.net/10481/28997] 1932-6203 doi: 10.1371/journal.pone.0023759 http://hdl.handle.net/10481/28997 eng http://creativecommons.org/licenses/by-nc-nd/3.0/ open access Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License Public Library of Science