<rdf:RDF xmlns:rdf="http://www.openarchives.org/OAI/2.0/rdf/" xmlns:ow="http://www.ontoweb.org/ontology/1#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:ds="http://dspace.org/ds/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:doc="http://www.lyncode.com/xoai" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/rdf/ http://www.openarchives.org/OAI/2.0/rdf.xsd">
   <ow:Publication rdf:about="oai:digibug.ugr.es:10481/111637">
      <dc:title>Medicago sativa L., a functional food to relieve hypertension and metabolic disorders in a spontaneously hypertensive rat model</dc:title>
      <dc:creator>Martínez Martínez, Rosario</dc:creator>
      <dc:creator>Kapravelou, Garyfallia</dc:creator>
      <dc:creator>Porres Foulquie, Jesús María</dc:creator>
      <dc:creator>Cantarero Malagón, Antonio Samuel</dc:creator>
      <dc:creator>Aranda Ramírez, Pilar</dc:creator>
      <dc:creator>López-Jurado Romero De La Cruz, María</dc:creator>
      <dc:subject>Alfalfa</dc:subject>
      <dc:subject>Blood pressure</dc:subject>
      <dc:subject>Polyphenols</dc:subject>
      <dc:subject>Glucagon-like peptide-1</dc:subject>
      <dc:subject>Spontaneously hypertensive rat</dc:subject>
      <dc:description>Medicago sativa L. (alfalfa) is a leguminous plant with beneficial effects on altered glucose&#xd;
and lipid metabolism, moreover exhibiting hypotensive activity. We improved the functional&#xd;
properties of alfalfa, growing the plant under specific soil conditions of high salinity.&#xd;
We determined the main bioactive compounds and five new phenolic compounds were identified.&#xd;
Alfalfa grown under high salinity conditions was added to experimental diets and&#xd;
assayed in an experimental model of spontaneously hypertensive rat. Among the main findings,&#xd;
a slight decrease on blood pressure, a reduction in the risk of kidney stone formation,&#xd;
a protective action against oxidative damage in fatty liver disease, as well as an improvement&#xd;
of glucose metabolism through the normalization of the gcg expression in colon should&#xd;
be underlined. Alfalfa can be used as an efficient functional food for the dietary prevention&#xd;
and treatment of several metabolic alterations, characteristic of the metabolic syndrome</dc:description>
      <dc:date>2026-02-27T07:50:49Z</dc:date>
      <dc:date>2026-02-27T07:50:49Z</dc:date>
      <dc:date>2016-10</dc:date>
      <dc:type>journal article</dc:type>
      <dc:identifier>Rosario Martínez, Garyfallia Kapravelou, Jesús M. Porres, Adela M. Melesio, Leticia Heras, Samuel Cantarero, Fiona M. Gribble, Helen Parker, Pilar Aranda, María López-Jurado, Medicago sativa L., a functional food to relieve hypertension and metabolic disorders in a spontaneously hypertensive rat model, Journal of Functional Foods, Volume 26, 2016, Pages 470-484, ISSN 1756-4646, https://doi.org/10.1016/j.jff.2016.08.013.</dc:identifier>
      <dc:identifier>https://hdl.handle.net/10481/111637</dc:identifier>
      <dc:identifier>https://doi.org/10.1016/j.jff.2016.08.013.</dc:identifier>
      <dc:language>eng</dc:language>
      <dc:rights>http://creativecommons.org/licenses/by-nc-nd/4.0/</dc:rights>
      <dc:rights>open access</dc:rights>
      <dc:rights>Attribution-NonCommercial-NoDerivatives 4.0 Internacional</dc:rights>
      <dc:publisher>Elsevier</dc:publisher>
   </ow:Publication>
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