Sulphur substituted 3-oxo-2,3-dihydropyridazine-4-carboxamides Carretero Coca, Rafael Small mollecule inhibitor Cancer AHR The present invention covers sulphur substituted 3-oxo-2,3-dihydropyridazine-4 carboxamide compounds of general formula (I): (I) in which R1, R2, A, X, Y and Z are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of cancer or conditions with 10 dysregulated immune responses or other disorders associated with aberrant AHR signaling, as a sole agent or in combination with other active ingredients. 2025-11-06T12:11:27Z 2025-11-06T12:11:27Z 2019-05-31 patent WO2019101642A1: Sulphur substituted 3-oxo-2,3-dihydropyridazine-4-carboxamides WO2019101642A1 https://hdl.handle.net/10481/107809 eng http://creativecommons.org/licenses/by-nc-nd/4.0/ open access Attribution-NonCommercial-NoDerivatives 4.0 Internacional WIPO/PCT