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   <ow:Publication rdf:about="oai:digibug.ugr.es:10481/107802">
      <dc:title>Expression of beta2-microglobulin as a prognostic marker for tumour immune escape and resistance to cancer immunotherapy and a diagnostic biomarker for patient selection for specific gene therapy</dc:title>
      <dc:creator>Carretero Coca, Rafael</dc:creator>
      <dc:subject>beta2-microglobulin</dc:subject>
      <dc:subject>B2m</dc:subject>
      <dc:subject>Immunotherapy</dc:subject>
      <dc:subject>Biomarker</dc:subject>
      <dc:subject>Cancer</dc:subject>
      <dc:subject>Gene therapy</dc:subject>
      <dc:description>The present invention refers to a method of predicting or prognosticating the response of a human subject to immunotherapy (from hereinafter method of the invention), wherein the subject is suffering from a cancer disease, and wherein the method comprises using, as an indicator, expression levels of p2-microglobulin from the tumour cells of a biological sample of the subject; wherein the result is indicative of a negative response if the expression levels of β2-microglobulin are under-expressed in comparison to a reference sample and/or a positive control. In a preferred embodiment of the invention, the expression levels are determined after said subject has been treated with immunotherapy.</dc:description>
      <dc:date>2025-11-06T11:07:09Z</dc:date>
      <dc:date>2025-11-06T11:07:09Z</dc:date>
      <dc:date>2014-06-26</dc:date>
      <dc:type>patent</dc:type>
      <dc:identifier>WO2014096367A1 - Expression of beta2-microglobulin as a prognostic marker for tumour immune escape and resistance to cancer immunotherapy and a diagnostic biomarker for patient selection for specific gene therapy</dc:identifier>
      <dc:identifier>WO2014096367A1</dc:identifier>
      <dc:identifier>https://hdl.handle.net/10481/107802</dc:identifier>
      <dc:language>eng</dc:language>
      <dc:rights>http://creativecommons.org/licenses/by-nc-nd/4.0/</dc:rights>
      <dc:rights>open access</dc:rights>
      <dc:rights>Attribution-NonCommercial-NoDerivatives 4.0 Internacional</dc:rights>
      <dc:publisher>WIPO (PCT)</dc:publisher>
   </ow:Publication>
</rdf:RDF>