Ultrasound-Guided Localization of the Refill Port for Intrathecal Infusion Pump Recharge: A Systematic Review Lechuga Carrasco, Beatriz Cordero Tous, Nicolás Reinoso-Cobo, Andrés Cortés-Martín, Jonathan Sánchez-García, Juan Carlos Rodríguez-Blanque, Raquel Gálvez Mateos, Rafael intrathecal infusion ultrasound refill port Background: Managing pain with intrathecal infusion pumps has significantly improved the treatment of individuals whose pain is uncontrollable by other methods. Using ultrasound to locate the refill port of these infusion pumps may offer an improvement over traditional methods. Objective: The objective of this systematic review is to update existing knowledge on the use of ultrasound for locating the refill port in intrathecal infusion pumps. Methods: The PRISMA review protocol was followed, and the review was registered in PROSPERO under registration number CRD 42024595671. Results: The main findings indicate that this technique is primarily used only in complex cases where access is difficult. Pain assessment, patient satisfaction, and recharge time compared to the traditional method are crucial factors for selecting the type of process to implement. Conclusions: No conclusive data are presented regarding the technique’s effect on pain reduction, patient satisfaction, reduction in time spent refilling the pump, or the prior experience level of the professional performing it, but notable improvements in these aspects are observed in certain situations. 2025-11-04T12:01:04Z 2025-11-04T12:01:04Z 2025-10-11 journal article Lechuga Carrasco, B.; Cordero Tous, N.; Reinoso-Cobo, A.; Cortés-Martín, J.; Sánchez-García, J.C.; Rodríguez-Blanque, R.; Gálvez Mateos, R. Ultrasound-Guided Localization of the Refill Port for Intrathecal Infusion Pump Recharge: A Systematic Review. J. Clin. Med. 2025, 14, 7178. https://doi.org/10.3390/jcm14207178 https://hdl.handle.net/10481/107759 10.3390/jcm14207178 eng http://creativecommons.org/licenses/by/4.0/ open access Atribución 4.0 Internacional MDPI