<rdf:RDF xmlns:rdf="http://www.openarchives.org/OAI/2.0/rdf/" xmlns:ow="http://www.ontoweb.org/ontology/1#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:ds="http://dspace.org/ds/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:doc="http://www.lyncode.com/xoai" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/rdf/ http://www.openarchives.org/OAI/2.0/rdf.xsd">
   <ow:Publication rdf:about="oai:digibug.ugr.es:10481/106518">
      <dc:title>Effects of manual therapy on oral opening, swallow function and upper quarter mobility in Chilean survivors of head and neck cancer: a study protocol for a controlled, randomised study (MAnual ThErapy for Oral Opening (MATEO) study)</dc:title>
      <dc:creator>Burgos Mansilla, Bárbara Lorena</dc:creator>
      <dc:creator>Schneeberger-Hitschfeld, Pilar</dc:creator>
      <dc:creator>Astete-Barra, Krishna</dc:creator>
      <dc:creator>Méndez-Rojas, Antonia</dc:creator>
      <dc:creator>Ortiz-Comino, Lucía</dc:creator>
      <dc:description>Introduction Head and neck cancer (HNC) accounts for&#xd;
over 4% of global cancer incidence, yet the oncological&#xd;
treatment induces several sequelae such as oral&#xd;
dysfunction, cervical and shoulder impairments or pain&#xd;
that are not well addressed. Thus, survivors of HNC (sHNC)&#xd;
perceive a decrease in their quality of life (QoL). This study&#xd;
protocol aims to investigate the effects of manual therapy&#xd;
(MT) to determine the effectiveness and safety on oral&#xd;
opening, swallow function and upper quarter mobility,&#xd;
cervical muscle strength, pain, functionality and QoL of&#xd;
sHNC.&#xd;
Methods and analysis A randomised controlled trial will&#xd;
include 70 sHNC over 18 years of age and will be divided&#xd;
into two groups. Intervention will last for 6 weeks with a&#xd;
total of 18 sessions, including MT targeting mastication&#xd;
and head and neck muscles. The control group will receive&#xd;
motor control exercises. The main outcomes will be&#xd;
oral opening and swallow function. An intention-to-treat&#xd;
analysis will be performed to evaluate the effectiveness of&#xd;
the intervention, which will be further determined with the&#xd;
calculation of effect sizes expressed in Cohen’s d.</dc:description>
      <dc:date>2025-09-22T08:47:11Z</dc:date>
      <dc:date>2025-09-22T08:47:11Z</dc:date>
      <dc:date>2025-09-02</dc:date>
      <dc:type>journal article</dc:type>
      <dc:identifier>Burgos-Mansilla, B., Schneeberger-Hitschfeld, P., Astete-Barra, K., Méndez-Rojas, A., &amp; Ortiz-Comino, L. (2025). Effects of manual therapy on oral opening, swallow function and upper quarter mobility in Chilean survivors of head and neck cancer: a study protocol for a controlled, randomised study (MAnual ThErapy for Oral Opening (MATEO) study). BMJ Open, 15(9), e097131. https://doi.org/10.1136/bmjopen-2024-097131</dc:identifier>
      <dc:identifier>https://hdl.handle.net/10481/106518</dc:identifier>
      <dc:identifier>10.1136/bmjopen-2024-097131</dc:identifier>
      <dc:language>eng</dc:language>
      <dc:rights>http://creativecommons.org/licenses/by-nc/4.0/</dc:rights>
      <dc:rights>open access</dc:rights>
      <dc:rights>Atribución-NoComercial 4.0 Internacional</dc:rights>
      <dc:publisher>BMJ Group</dc:publisher>
   </ow:Publication>
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