Extraction Methods of Emerging Pollutants in Sewage Sludge: A Comprehensive Review Robledo-Mahón, Tatiana Mercl, Filip Sridhara Chary, Nallanthigal Száková, Jiřina Tlustoš, Pavel Emerging pollutants Sewage sludge Extraction methods Sewage sludge (SS) is commonly applied as a soil amendment. This practice has raised concern about the dissemination of emerging pollutants (EPs). EPs include compounds such as flame retardants, plasticizers, pharmaceuticals, and personal care products, among others, which may pose risks to human health and ecosystems. The complexity of the SS matrix, combined to the absence of an international legislation framework, makes it necessary to evaluate the techniques available for detecting these contaminants. Detection is typically performed using sensitive analytical techniques; however, the extraction strategy selected remains a crucial step. This review aims to compile different methodologies for the determination of EPs in SS, focusing on extraction strategies reported between 2010 and 2025. Ultrasound-assisted extraction (UAE), pressurized liquid extraction (PLE), and microwaveassisted extraction (MAE) are the most widely used strategies for EPs. UAE is considered the most preferable option, as it enables the extraction of a wide range of compounds without the need for expensive equipment. Among novel techniques, the quick, easy, cheap, effective, rugged, and safe (QuEChERS) method is especially promising, as it is applicable to multiple target compounds. This review provides up-to-date information that can support the development of routine and standardized methodologies for the characterization of EPs in SS. 2025-09-19T08:12:17Z 2025-09-19T08:12:17Z 2025-08-05 journal article Robledo-Mahón, T.; Mercl, F.; Chary, N.S.; Száková, J.; Tlustoš, P. Extraction Methods of Emerging Pollutants in Sewage Sludge: A Comprehensive Review. Toxics 2025, 13, 661. https://doi.org/10.3390/toxics13080661 https://hdl.handle.net/10481/106462 10.3390/toxics13080661 eng http://creativecommons.org/licenses/by/4.0/ open access Atribución 4.0 Internacional MDPI