Impact of SARS-COV-2 Infection on Maternal, Obstetric and Neonatal Outcomes in a Cohort of Vaccinated Women: A Pilot Study Cruz Calvente, María Rueda Medina, Blanca María Gil Gutiérrez, María del Rocío Medina Martínez, Irene Gómez Urquiza, Jose Luis Correa Rodríguez, María COVID-19 SARS-CoV-2 birth plan breast feeding neonatal nursing obstetric nursing prenatal education This work is part of María Cruz-Calvente doctoral work at the Clinical Medicine and Public Health doctoral studies program of the University of Granada, Granada, Spain. We aimed to investigate the impact of COVID-19 infection on maternal characteristics and obstetric and neonatal outcomes in a cohort of women in labor previously vaccinated who tested positive for SARS-CoV-2 infection, compared to aged-matched healthy controls. A retrospective case-control study was conducted among 66 women in labor. Clinical data were obtained from medical records. The attendance rates at childbirth and parenting classes, as well as the implementation of a birth plan, were significantly lower in the COVID-19 infection group (6.1% vs. 48.5%, <0.001; 6.1% vs. 33.3%, p = .005, respectively). Women with COVID-19 had a higher prevalence of prolonged postpartum hospital stay (33.3% vs. 9.1%, p = .016), and significantly higher prevalence of spontaneous preterm birth (27.3% vs. 1.09%, p = .006). Breastfeeding within the first 24 hr was also lower in women with COVID-19 (72.7% vs. 97.0%, p = .006). Maternal characteristics and neonatal outcomes are influenced by COVID-19 infection in vaccinated women. Complications include spontaneous preterm birth, prolonged postpartum hospital stay, and lack of breastfeeding within the first 24 hr. Childbirth education, parenting classes and implementing a birth plan may be associated with a decreased risk of COVID-19 infection. 2025-06-24T09:45:56Z 2025-06-24T09:45:56Z 2024-07 journal article Cruz-Calvente, M., Rueda-Medina, B., Gil-Gutiérrez, R., Medina-Martínez, I., Gómez-Urquiza, J. L., & Correa-Rodríguez, M. (2024). Impact of SARS-COV-2 Infection on Maternal, Obstetric and Neonatal Outcomes in a Cohort of Vaccinated Women: A Pilot Study. Biological research for nursing, 26(3), 429–437. https://doi.org/10.1177/10998004241237134 https://hdl.handle.net/10481/104806 10.1177/10998004241237134 eng http://creativecommons.org/licenses/by-nc-nd/3.0/ open access Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License Sage