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      <dc:title>Effects of exercise-based interventions on health-related quality of life in adults after cancer: A systematic review and meta-analysis</dc:title>
      <dc:creator>Mármol-Pérez, Andrés</dc:creator>
      <dc:creator>Gracia Marco, Luis Andrés</dc:creator>
      <dc:creator>Clavero-Jimeno, Antonio</dc:creator>
      <dc:creator>Amaro Gahete, Francisco José</dc:creator>
      <dc:creator>Ruiz Ruiz, Jonatan</dc:creator>
      <dc:creator>Carneiro Barrera, Almudena</dc:creator>
      <dc:description>Supplementary materials&#xd;
Download: Download Word document (527KB)&#xd;
https://ars.els-cdn.com/content/image/1-s2.0-S1877065725000193-mmc1.docx</dc:description>
      <dc:description>Background&#xd;
Due to the lack of available knowledge in the current literature, this systematic review and meta-analysis was aimed to assess the effectiveness of exercise-based lifestyle interventions, including healthy diet and/or psychological well-being on mental, physical and global health-related quality of life (HRQoL) in adults after cancer treatment.&#xd;
Methods&#xd;
MEDLINE (via PubMed) and Web of Science databases were searched for randomised controlled trials (RCTs) published until August 2024 evaluating exercise-based lifestyle interventions, including healthy diet and/or psychological well-being, which assessed mental, physical and global HRQoL.&#xd;
Results&#xd;
Of 6193 screened studies, 32 RCTs met the criteria. The total sample comprised 5528 participants (3003 intervention and 2525 control). There was a small effect size in a pooled analysis that found exercise-based lifestyle interventions improve mental HRQoL (d 0.11, 95 % CI 0.05 to 0.18). These effects were greater in those studies that combined exercise with psychological well-being (d = 0.19, P = 0.004), and with moderate-to-high intensity aerobic exercise (moderate intensity; d = 0.11, P = 0.02, high intensity; d = 0.16, P = 0.02, aerobic exercise; d = 0.16, P = 0.26).&#xd;
Conclusions&#xd;
Exercise-based lifestyle interventions do not enhance physical nor global HRQoL, yet those combined with psychological well-being seem to improve mental HRQoL in individuals after cancer treatment.</dc:description>
      <dc:date>2025-04-23T06:52:08Z</dc:date>
      <dc:date>2025-04-23T06:52:08Z</dc:date>
      <dc:date>2025-04-18</dc:date>
      <dc:type>journal article</dc:type>
      <dc:identifier>Marmol-Perez A, Gracia-Marco L, Clavero-Jimeno A, Amaro-Gahete FJ, Ruiz JR, Carneiro-Barrera A. Effects of exercise-based interventions on health-related quality of life in adults after cancer: A systematic review and meta-analysis. Ann Phys Rehabil Med. 2025 Apr 18;68(5):101954. doi: 10.1016/j.rehab.2025.101954</dc:identifier>
      <dc:identifier>https://hdl.handle.net/10481/103739</dc:identifier>
      <dc:identifier>10.1016/j.rehab.2025.101954</dc:identifier>
      <dc:language>eng</dc:language>
      <dc:rights>http://creativecommons.org/licenses/by-nc-nd/4.0/</dc:rights>
      <dc:rights>open access</dc:rights>
      <dc:rights>Attribution-NonCommercial-NoDerivatives 4.0 Internacional</dc:rights>
      <dc:publisher>Elsevier</dc:publisher>
   </ow:Publication>
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