<rdf:RDF xmlns:rdf="http://www.openarchives.org/OAI/2.0/rdf/" xmlns:ow="http://www.ontoweb.org/ontology/1#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:ds="http://dspace.org/ds/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:doc="http://www.lyncode.com/xoai" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/rdf/ http://www.openarchives.org/OAI/2.0/rdf.xsd">
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      <dc:title>Quality of Life and Mental Health Well-Being in Sjögren’s Disease in the UK: A Cross-Sectional Comparative Analysis</dc:title>
      <dc:creator>Al-Ezzi, Minan Y.</dc:creator>
      <dc:creator>Khan, Khalid Saeed</dc:creator>
      <dc:creator>Tappuni, Anwar R.</dc:creator>
      <dc:subject>Quality of life</dc:subject>
      <dc:subject>Oral health-related quality of life</dc:subject>
      <dc:subject>Anxiety</dc:subject>
      <dc:subject>Depression</dc:subject>
      <dc:subject>Sjögren’s disease</dc:subject>
      <dc:description>This work was funded by the Ministry of Higher Education and Scientific Research in Iraq, in partial fulfilment of the requirements for a PhD degree.</dc:description>
      <dc:description>Objectives: We aimed to evaluate the quality of life (QoL), oral health-related quality of life (OHRQoL), and mental health well-being in female patients diagnosed with Sjögren’s Disease compared with healthy controls. Methods: An ethically approved cross-sectional study was carried out on 65 female patients with a confirmed diagnosis of Sjögren’s Disease according to the American European Association Consensus Group Criteria and 61 sex-matched healthy volunteers. The World Health Organization Quality of Life-BREF, Oral Health Impact Profile-14, and Hospital Anxiety and Depression Scale were used to evaluate the general and oral health-related QoL (OHRQoL) and the mental health well-being of the participants. Results: The general QoL was lower in the patients’ group (p &lt; 0.05) compared with the control group in all four domains (physical, psychological, social, and environment). The OHRQoL was significantly reduced in the patients’ group, who were more anxious (58.5%, n = 38/65) and four times more depressed (32.3%, n = 21/65) compared with healthy volunteers (anxiety = 21%, n = 13/61; depression = 8.2%, n = 5/61). Conclusions: This study concludes that Sjögren’s Disease negatively affects QoL and mental well-being. Therefore, addressing these aspects in patients’ management is crucial to helping individuals cope with the disease’s burden and ultimately enhancing their overall life experience.</dc:description>
      <dc:date>2025-03-26T08:14:39Z</dc:date>
      <dc:date>2025-03-26T08:14:39Z</dc:date>
      <dc:date>2025-03-13</dc:date>
      <dc:type>journal article</dc:type>
      <dc:identifier>Al-Ezzi, M.Y.; Khan, K.S.; Tappuni, A.R. Quality of Life and Mental Health Well-Being in Sjögren’s Disease in the UK: A Cross-Sectional Comparative Analysis. J. Clin. Med. 2025, 14, 1939. https://doi.org/10.3390/jcm14061939</dc:identifier>
      <dc:identifier>https://hdl.handle.net/10481/103293</dc:identifier>
      <dc:identifier>10.3390/jcm14061939</dc:identifier>
      <dc:language>eng</dc:language>
      <dc:rights>http://creativecommons.org/licenses/by/4.0/</dc:rights>
      <dc:rights>open access</dc:rights>
      <dc:rights>Atribución 4.0 Internacional</dc:rights>
      <dc:publisher>MDPI</dc:publisher>
   </ow:Publication>
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