Electrophysiological evidence for domain-general processes in task-switching Capizzi, Mariagrazia Ambrosini, Ettore Arbula, Sandra Mazzonetto, Ilaria Vallesi, Antonino The ability to flexibly switch between tasks is a hallmark of cognitive control. Despite previous studies that have investigated whether different task-switching types would be mediated by distinct or overlapping neural mechanisms, no definitive consensus has been reached on this question yet. Here, we aimed at directly addressing this issue by recording the event-related potentials (ERPs) elicited by two types of task-switching occurring in the context of spatial and verbal cognitive domains. Source analysis was also applied to the ERP data in order to track the spatial dynamics of brain activity underlying task-switching abilities. In separate blocks of trials, participants had to perform either spatial or verbal switching tasks both of which employed the same type of stimuli. The ERP analysis, which was carried out through a channel- and time-uninformed mass univariate approach, showed no significant differences between the spatial and verbal domains in the modulation of switch and repeat trials. Specifically, relative to repeat trials, switch trials in both domains were associated with a first larger positivity developing over left parieto-occipital electrodes and with a subsequent larger negativity distributed over mid-left fronto-central sites. The source analysis reconstruction for the two ERP components complemented these findings by highlighting the involvement of left-lateralized prefrontal areas in task-switching. Overall, our results join and extend recent research confirming the existence of left-lateralized domain-general task-switching processes. 2025-01-24T07:44:29Z 2025-01-24T07:44:29Z 2016 journal article Capizzi, M., Ambrosini, E., Arbula, S., Mazzonetto, I., & Vallesi, A. (2016). Electrophysiological Evidence for Domain-General Processes in Task-Switching. Frontiers in human neuroscience, 10, 124. https://doi.org/10.3389/fnhum.2016.00124 https://hdl.handle.net/10481/100192 10.3389/fnhum.2016.00124 eng The authors are supported by the European Research Council under the European Union’s 7th Framework Programme (FP7/2007-2013)/ERC grant agreement n° 313692 awarded to AV. http://creativecommons.org/licenses/by-nc-nd/4.0/ open access Attribution-NonCommercial-NoDerivatives 4.0 Internacional Frontiers