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A multi-valent polymyxin-based fluorescent probe for the detection of Gram-negative infections†

dc.contributor.authorSharma, Richa
dc.contributor.authorRodriguez Rios, Maria
dc.contributor.authorCrossland, James
dc.contributor.authorSeptiyana, Maulida
dc.contributor.authorMegia-Fernandez, Alicia 
dc.contributor.authorKlausen, Maxime
dc.contributor.authorBradley, Mark
dc.date.accessioned2025-01-07T11:43:51Z
dc.date.available2025-01-07T11:43:51Z
dc.date.issued2024-12-17
dc.identifier.citationSharma, R. et. al. J. Mater. Chem. B, 2025. [https://doi.org/10.1039/d4tb01786b]es_ES
dc.identifier.urihttps://hdl.handle.net/10481/98502
dc.description.abstractAmulti-branched fluorogenic probe for the rapid and specific detection of Gram-negative bacteria is reported. ThreeGram-negative-targeting azidomodified polymyxins were clicked onto a trivalent scaffold functionalised with the environmental green-emitting fluorophore 7-nitrobenz-2-oxa- 1,3-diazole. The probe allowedwash-free detection of target bacteriawith increased sensitivity and lower limits of detection compared to monovalent probes.es_ES
dc.language.isoenges_ES
dc.publisherRoyal Society of Chemistryes_ES
dc.rightsAtribución 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.titleA multi-valent polymyxin-based fluorescent probe for the detection of Gram-negative infections†es_ES
dc.typejournal articlees_ES
dc.rights.accessRightsopen accesses_ES
dc.identifier.doi10.1039/d4tb01786b
dc.type.hasVersionVoRes_ES


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