Mostrar el registro sencillo del ítem

dc.contributor.authorTriguero Cueva, Lucía
dc.contributor.authorMarín Romero, Bartolomé
dc.contributor.authorMadrid Navarro, Carlos Javier
dc.contributor.authorPérez Navarro, Maria José
dc.contributor.authorIáñez Velasco, Benjamín
dc.contributor.authorMínguez Castellanos, Adolfo
dc.contributor.authorJouma Katati, Majed 
dc.contributor.authorEscamilla-Sevilla, Francisco
dc.date.accessioned2024-11-22T07:53:00Z
dc.date.available2024-11-22T07:53:00Z
dc.date.issued2023-10-30
dc.identifier.citationTriguero-Cueva L, Marín-Romero B, Madrid-Navarro CJ, Pérez-Navarro MJ, Iáñez-Velasco B, Mínguez-Castellanos A, Katati MJ and Escamilla-Sevilla F (2023) Neuropsychological assessment protocol in an ongoing randomized controlled trial on posterior subthalamic area vs. ventral intermediate nucleus deep brain stimulation for essential tremor. Front. Neurol. 14:1222592. doi: 10.3389/fneur.2023.1222592es_ES
dc.identifier.urihttps://hdl.handle.net/10481/97237
dc.description.abstractObjective: Patients with essential tremor (ET) may experience cognitive-affective impairment. Deep brain stimulation (DBS) of different targets, such as the ventral intermediate nucleus (VIM) of the thalamus or the posterior subthalamic area (PSA), has been shown to be beneficial for refractory ET. However, there is little evidence regarding the possible neuropsychological effects of PSA-DBS on patients with ET, and there are few studies comparing it with VIM-DBS in this population. In this study, we aim to present the evaluation protocol and neuropsychological battery as used in an ongoing trial of DBS for ET comparing the already mentioned targets. Methods: As part of a randomized, double-blind, crossover clinical trial comparing the effectiveness and safety of PSA-DBS vs. VIM-DBS, 11 patients with refractory ET will undergo a multi-domain neuropsychological battery assessment. This will include a pre−/post-implantation assessment (3 months after the stimulation of each target and 6 months after an open stage of DBS on the most optimal target). Conclusion: Evidence on the neuropsychological effects of DBS in patients with refractory ET is very scarce, particularly in lesser-explored targets such as PSA. This study could contribute significantly in this field, particularly on pre-procedure safety analysis for tailored patient/technique selection, and to complete the safety analysis of the procedure. Moreover, if proven useful, this proposed neuropsychological assessment protocol could be extensible to other surgical therapies for ET.es_ES
dc.description.sponsorshipInstituto de Salud Carlos IIIes_ES
dc.description.sponsorshipEuropean Regional Development Fund (PI19/01571)es_ES
dc.language.isoenges_ES
dc.publisherFrontiers Mediaes_ES
dc.rightsAtribución 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectcognitive-affective impairmentes_ES
dc.subjectdeep brain stimulationes_ES
dc.subjectessential tremores_ES
dc.titleNeuropsychological assessment protocol in an ongoing randomized controlled trial on posterior subthalamic area vs. ventral intermediate nucleus deep brain stimulation for essential tremores_ES
dc.typejournal articlees_ES
dc.rights.accessRightsopen accesses_ES
dc.identifier.doi10.3389/fneur.2023.1222592
dc.type.hasVersionVoRes_ES


Ficheros en el ítem

[PDF]

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem

Atribución 4.0 Internacional
Excepto si se señala otra cosa, la licencia del ítem se describe como Atribución 4.0 Internacional