Safety and Effectiveness of Percutaneous Ultrasound- Guided Galvanic Current in Tunnels of Patients with Hidradenitis Suppurativa: A Pilot Study
Metadatos
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Soto Moreno, Alberto; Cuenca Barrales, Carlos; Arias Santiago, Salvador Antonio; García-Vidal, José Antonio; Medina-Mirapeix, Francesc; Molina Leyva, AlejandroEditorial
SpringerLink
Materia
Hidradenitis suppurativa Galvanic current Intralesional therapy
Fecha
2024-04-27Referencia bibliográfica
Soto Moreno, A. et. al. Dermatol Ther (Heidelb) 14, 1115–1125 (2024). [https://doi.org/10.1007/s13555-024-01149-5]
Resumen
Introduction: The recurrent nature of
hidradenitis suppurativa (HS), even under
maintained systemic treatment, makes it necessary
to have effective local treatments; however,
the response to these therapies is variable
(44–81%). The application of galvanic current
(GC) has demonstrated its utility in humans in
treating lesions structurally similar to those of
HS. With this background, the main objective
of this study was to evaluate the efficacy and
safety of ultrasound-guided percutaneous GC in
inflamed and/or draining tunnels of HS.
Methods: This was an open study (one-way
repeated measures design over time). Patients
were evaluated at 4 and 12 weeks after receiving
GC. A combined clinical response at week 12
(absence of suppuration/inflammation on
examination and clinical interview) was considered
the principal variable of efficacy.
Adverse effects potentially associated with GC
were reported by telephone and at each visit.
Results: Twenty-six patients were included,
with a male/female ratio of 5:8. The mean age
was 35.84 (13.14) years. At 12 weeks after the
administration of GC, a complete response was
achieved in 77% (20/26) of the treated lesions.
No serious adverse effects were observed, and
the mean procedural pain assessed by the
numeric rating scale was 0.03 (0.2).
Conclusion: GC has proven to be effective and
well tolerated in inflamed and draining tunnels
of patients with HS.