Siderophores and competition for iron govern myxobacterial predation dynamics
Metadatos
Mostrar el registro completo del ítemAutor
Contreras Moreno, Francisco Javier; Moraleda Muñoz, Aurelio; Marcos Torres, Francisco Javier; Cuéllar, Victoria; Soto, María José; Pérez Torres, Juana; Muñoz Dorado, JoséEditorial
Oxford University Press
Materia
Myxococcus xanthus Sinorhizobium meliloti Iron competition Myxochelins Rhizobactin 1021
Fecha
2024-05-02Referencia bibliográfica
Contreras-Moreno FJ, Moraleda-Muñoz A, Marcos-Torres FJ, Cuéllar V, Soto MJ, Pérez J, Muñoz-Dorado J. Siderophores and competition for iron govern myxobacterial predation dynamics. ISME J. 2024 Jan 8;18(1):wrae077. doi: 10.1093/ismejo/wrae077. PMID: 38696719; PMCID: PMC11388931.
Patrocinador
PID2020-112634GB-I00 (to A.M.M. and J.M.D.) funded by MCIN/AEI/ 10.13039/501100011033; PGC2018-096477-B-I00 and PID2021-123540NB-I00 (to M.J.S.) funded by MCIN/AEI/10.13039/501100011033 and by “ERDF A way of making Europe”; A-BIO-126-UGR20 (to J.P. and A.M.M.) funded by Consejería de Universidad, Investigación e Innovación de la Junta de Andalucía and by “ERDF A way of making Europe”; Marie Skłodowska-Curie Action (MSCA) grant LysM Ref. 101106411 (to F.J.M.T. and J.M.D.)Resumen
Bacterial predators are decisive organisms that shape microbial ecosystems. In this study, we investigated the role of iron and siderophores during the predatory interaction between two rhizosphere bacteria: Myxococcus xanthus, an epibiotic predator, and Sinorhizobium meliloti, a bacterium that establishes nitrogen-fixing symbiosis with legumes. The results show that iron enhances the motility of the predator and facilitates its predatory capability, and that intoxication by iron is not used by the predator to prey, although oxidative stress increases in both bacteria during predation. However, competition for iron plays an important role in the outcome of predatory interactions. Using combinations of predator and prey mutants (nonproducers and overproducers of siderophores), we have investigated the importance of competition for iron in predation. The results demonstrate that the competitor that, via the production of siderophores, obtains sufficient iron for growth and depletes metal availability for the opponent will prevail in the interaction. Consequently, iron fluctuations in soils may modify the composition of microbial communities by altering the activity of myxobacterial predators. In addition, siderophore overproduction during predation can alter soil properties, affecting the productivity and sustainability of agricultural operations.