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Characterization of daptomycin non-susceptible Enterococcus faecium producing urinary tract infection in a renal transplant recipient
dc.contributor.author | Solorzano Puerto, Antonio | |
dc.contributor.author | Panesso, Diana | |
dc.contributor.author | Navarro-Marí, José María | |
dc.contributor.author | Arias, Cesar A | |
dc.contributor.author | Gutiérrez Fernández, José | |
dc.date.accessioned | 2024-05-15T10:13:40Z | |
dc.date.available | 2024-05-15T10:13:40Z | |
dc.date.issued | 2015-08 | |
dc.identifier.citation | Sorlózano A, Panesso D, Navarro-Marí JM, Arias CA, Gutiérrez-Fernández J. Characterization of daptomycin non-susceptible Enterococcus faecium producing urinary tract infection in a renal transplant recipient. Rev Esp Quimioter. 2015 Aug;28(4):207-9. | es_ES |
dc.identifier.other | PMID: 26200029 | |
dc.identifier.uri | https://hdl.handle.net/10481/91815 | |
dc.description.abstract | Objectives: Characterization of a urine isolate of daptomycin non-susceptible Enterococcus faecium recovered from a patient with kidney transplantation and no history of daptomycin exposure. Methods: After isolation in a urine sample, identification of E. faecium was confirmed by amplification of the E. faecium-specific gene encoding D-alanyl-D-alanine ligase (ddl) and daptomycin susceptibility testing was performed by E-test on cation-adjusted Mueller-Hinton agar. In order to determine the genetic bases of daptomycin resistance, the open reading frames of five genes previously associated with daptomycin resistance in enterococci were sequenced. Results: Substitutions in the response regulator LiaR (S19F) and cardiolipin synthase (R218Q) were identified. Conclusions: To the best of our knowledge, this is the first characterization of emerging daptomycin resistance in E. faecium in a Spanish hospital in the absence of daptomycin exposure and in a renal transplant recipient. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Rev Esp Quimioter . | es_ES |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.title | Characterization of daptomycin non-susceptible Enterococcus faecium producing urinary tract infection in a renal transplant recipient | es_ES |
dc.title.alternative | Caracterización de enterococcus faecium no sensible a daptomicina produciendo infección del tracto urinario en un paciente trasplantado renal | es_ES |
dc.type | journal article | es_ES |
dc.rights.accessRights | open access | es_ES |