Preliminary readings of antimicrobial susceptibility panels: A simple, fast and inexpensive way to detect bacterial resistance and enhance antibiotic treatment of bloodstream infections
Metadatos
Afficher la notice complèteAuteur
Sánchez Yebra, Waldo; Obelleiro Campos, Alexandre Xabier; Del Gigia Aguirre, Laura; Cabezas Fernández, Teresa; Sánchez Gómez, Juan; De Lamo Sevilla, Cristina; Gutiérrez Fernández, José; Rodríguez Maresca, ManuelEditorial
Elsevier
Date
2019-08Referencia bibliográfica
W. Sánchez Yebra et al. Preliminary readings of antimicrobial susceptibility panels: A simple, fast and inexpensive way to detect bacterial resistance and enhance antibiotic treatment of bloodstream infections. Diagnostic Microbiology and Infectious Disease 94 (2019) 398–402. https://doi.org/10.1016/j.diagmicrobio.2019.03.001
Résumé
Increasing incidence of resistant bacteria needs faster identification (ID) and antibiotic susceptibility testing (AST) in order to improve antimicrobial treatment of severe infections. We propose a preliminary reading of the AST MicroScan® panels coupled with mass spectrometry ID. A total of 157 bacterial clinical isolates were processed for routine ID and AST (in 22 cases, ID and AST were performed directly from positive blood culture bottles). For gram-negatives, data from the initial and final readings were recorded and compared [89.9% category agreement (CA), 6.9% very major errors (VME)]. In adition all the 32 ESBL producers were detected at 5.3-8.6 hours. For Staphylococcus aureus, all the 16 MRSA isolates were detected at 4.5 to 7.5 hours. Thus, we find our preliminary readings approach as a simple, inexpensive and reliable way to detect and identify the most prevalent resistant bacteria in our institution on the same day that ID/AST is performed.