Patrón de sensibilidad de las Aeromonas spp. productoras de infecciones extraintestinales

Abstract

We studied the sensibility to several antimicrobics of aeromonas strains isolated in extraintestinal infections during a period of five years, in order to establish which could be the best empirical therapy in these processes. Twenty-two strains of A. hydrophila were evaluated, was isolated (8 from hemocultures, 6 from wound exudate, 2 from abscess aspirate, 2 from peritoneal fluid and 1 from urine, pleural fluid, bile and catheter). The identification was made using the GNI card System (Vitek System) and other tests. The sensibility was assessed using the GNS-BH and GNS-BI card System (Vitek), which allows to know the clinical category and CMI value in microgram/ml. All the strains presented some resistance to antibiotics. 77.8% of the strains were resistant to more than one antibiotic and 64.9%, to more than two antibiotics. We detected 21.7% strains resistant to 4 drugs. The most frequent resistance association was ampicillin, cephoxitine, cephazoline, cephalotine, with or without amoxicillin and clavulanic acid. All the strains were sensible to cephamandol, cephuroxime, cephtriaxone, cephtazidime, cephotaxime, thicarciline, aztreonam, azlociline, mezlociline, piperaciline, gentamycin, amikacine, chloranphenicol and ciprofloxacine. All the strains were resistant to ampicillin; 60.9% of the strains were sensible to the association amoxicillin and clavulonic acid. In conclusion, the treatment of extraintestinal infections does not differs basically from the treatment of the infections caused by Gram-negative bacillus. There are a broad range of effective antibiotics: aminoglycosides (gentamycin, tobramycin, amikacine), piperacyline, cephalosporines (cephuroxime, cephotaxime, cephtazidime and cephtriaxone), chloranphenicol, penemas, monobactanes of fluorquinolone.