Mostrar el registro sencillo del ítem
Evolution of the resistance to antibiotics of bacteria involved in urinary tract infections: a 7-year surveillance study
dc.contributor.author | Sorlozano Puerto, Antonio | |
dc.contributor.author | Jiménez Pacheco, Antonio | |
dc.contributor.author | Luna Del Castillo, Juan De Dios | |
dc.contributor.author | Sampedro, Antonio | |
dc.contributor.author | Martínez Brocal, Antonio | |
dc.contributor.author | Miranda-Casas, Consuelo | |
dc.contributor.author | Navarro Marí, José María | |
dc.contributor.author | Gutiérrez Fernández, José | |
dc.date.accessioned | 2024-03-14T11:43:51Z | |
dc.date.available | 2024-03-14T11:43:51Z | |
dc.date.issued | 2014-10 | |
dc.identifier.citation | Sorlozano A, Jimenez-Pacheco A, de Dios Luna Del Castillo J, Sampedro A, Martinez-Brocal A, Miranda-Casas C, Navarro-Marí JM, Gutiérrez-Fernández J. Evolution of the resistance to antibiotics of bacteria involved in urinary tract infections: a 7-year surveillance study. Am J Infect Control. 2014 Oct;42(10):1033-8. https://doi.org/10.1016/j.ajic.2014.06.013 | es_ES |
dc.identifier.uri | https://hdl.handle.net/10481/89977 | |
dc.description.abstract | Background: We conducted a retrospective analysis on the identification and antibiogram of all bacteria isolated from urine samples with microbiological confirmation of urinary tract infection (UTI) in a Spanish reference hospital over a 7-year period. Methods: A retrospective analysis was performed of the identification and antibiogram data. Results: A total of 31,758 uropathogens were isolated. Escherichia coli accounted for the majority (55.2%) of these, followed by Enterococcus faecalis (18.0%) and Klebsiella spp (10.3%). The highest E coli susceptibility rates were to imipenem (93.0%-99.8%), amikacin (97.3%-99.5%), nitrofurantoin (96.7%-98.9%), and fosfomycin (95.3%-100%), and the lowest were to cefuroxime (67.8%-86.4%), ciprofloxacin (61.2%-69.8%), and co-trimoxazole (55.0%-65.5%). We highlight the overall high activity of imipenem, piperacillin-tazobactam, nitrofurantoin, and fosfomycin on isolates versus the low activity of fluoroquinolones, co-trimoxazole, or cephalosporins. The activity of amoxicillin-clavulanic acid and fosfomycin decreased significantly over the 7-year study period. Conclusions: Imipenem and piperacillin-tazobactam appear to be good options for the empiric treatment of UTI acquired in hospital or requiring hospitalization, whereas nitrofurantoin and fosfomycin can be first-choice antibiotics for the treatment of uncomplicated community-acquired cystitis. However, surveillance studies are required to detect resistance to these antibiotics, given that an increase in uropathogen resistance rates may contraindicate its future use in empiric UTI therapy. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Elsevier | es_ES |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Antimicrobial resistance | es_ES |
dc.subject | Antibiotic susceptibility | es_ES |
dc.subject | Urine analysis | es_ES |
dc.subject | Infection control | es_ES |
dc.title | Evolution of the resistance to antibiotics of bacteria involved in urinary tract infections: a 7-year surveillance study | es_ES |
dc.type | journal article | es_ES |
dc.rights.accessRights | open access | es_ES |
dc.identifier.doi | 10.1016/j.ajic.2014.06.013 | |
dc.type.hasVersion | VoR | es_ES |