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dc.contributor.authorTejada, Sofía
dc.contributor.authorBaca García, María Pilar 
dc.contributor.authorFerrer Luque, Carmen María 
dc.contributor.authorRuiz Linares, Matilde 
dc.contributor.authorValderrama Bonnet, Mariano José 
dc.contributor.authorArias Moliz, María Teresa 
dc.date.accessioned2024-01-26T13:23:23Z
dc.date.available2024-01-26T13:23:23Z
dc.date.issued2018-08-02
dc.identifier.citationTejada S, Baca P, Ferrer-Luque CM, Ruiz-Linares M, Valderrama MJ, Arias-Moliz MT. Influence of dentine debris and organic tissue on the properties of sodium hypochlorite solutions. Int Endod J. 2019 Jan;52(1):114-122.es_ES
dc.identifier.urihttps://hdl.handle.net/10481/87391
dc.description.abstractAim: To determine the free available chlorine of 2.5% sodium hypochlorite (NaOCl) alone and combined with 9% etidronic acid (HEDP) in the presence of inhibitors, organic tissue and organic tissue plus dentine debris; to evaluate the influence of dentine debris on the tissue-dissolving capacity of both NaOCl solutions; and to determine the antimicrobial action of these solutions when in contact with organic tissue and organic tissue plus dentine debris. Methodology: The available chlorine of the solutions over time in the absence and presence of the inhibitors was measured using a titration method. The organic tissue dissolution by the solutions alone and in the presence of dentine powder was evaluated by weighing bovine tissue specimens before and after exposure to the solutions for 3 and 10 min. For the antimicrobial activity, biofilms of Enterococcus faecalis were exposed to the solutions for 3 min in the absence and presence of organic tissue and organic tissue + dentine debris. The biovolume and percentage of damaged membrane cells of the biofilm were measured by means of confocal microscopy and the live/dead technique. Nonparametric tests were used to determine statistical differences (P < 0.05). Results: Both inhibitors consumed the free available chlorine of the solutions over time. The presence of dentine debris significantly reduced the tissue dissolution capacity of the NaOCl solutions (P < 0.05). The percentages of biovolume reduction were not affected by the presence of the inhibitors in the two NaOCl solutions, whereas the percentage of damaged membrane cells was significantly reduced (P < 0.001). Overall, a similar behaviour was observed in the NaOCl and NaOCl/HEDP groups. Conclusions: The presence of organic tissue and organic tissue + dentine debris favoured rapid consumption of the free chlorine of NaOCl and NaOCl/HEDP. This resulted in a decreased ability to dissolve organic tissue without affecting the short-term antimicrobial activity.es_ES
dc.description.sponsorshipGrupo CTS 167es_ES
dc.language.isoenges_ES
dc.publisherWileyes_ES
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.titleInfluence of dentine debris and organic tissue on the properties of sodium hypochlorite solutionses_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES
dc.identifier.doi10.1111/iej.12986
dc.type.hasVersioninfo:eu-repo/semantics/draftes_ES


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