The association of adolescent fitness with cardiometabolic diseases in late adulthood: A 45-year longitudinal study
Metadata
Show full item recordEditorial
Wiley
Materia
Adolescence Cardiometabolic disease Cohort study Longitudinal Physical fitness
Date
2023-10-31Referencia bibliográfica
Laakso PTT, Ortega FB, Huotari P, Tolvanen AJ, Kujala UM, Jaakkola TT. The association of adolescent fitness with cardiometabolic diseases in late adulthood: A 45-year longitudinal study. Scand J Med Sci Sports. 2023;00:1-11. [doi: 10.1111/sms.14529]
Sponsorship
Emil Aaltonen Foundation 210097 O; Ellen ja Artturi Nyyssönen Foundation; Juho Vainio Foundation 202300290Abstract
Objectives: The aim of this study was to examine the associations of adolescent
cardiorespiratory fitness (CRF), muscular fitness (MF), and speed-agility fitness
(SA) with middle-aged cardiometabolic disease risk and explore sex differences.
Methods: This 45-year prospective cohort study examined the associations be-
tween objectively measured fitness at adolescence (12–19 years) and physician-
ascertained diabetes mellitus, elevated blood pressure (BP), and coronary heart
disease reported either in early (37–44 years) or late (57–64 years) middle age, and
self-measurement of waist circumference (WC) in late middle age. Fitness meas-
urements for healthy adolescents in baseline included CRF (1.5 km [girls] and
2 km [boys] run), MF (standing broad jump, sit-ups, pull-ups [boys], and flexed-
arm hang [girls]), and SA (50 m dash and 4 × 10 m shuttle run). Logistic regression
and general linear models were adjusted for baseline age, sex, and body mass
index (BMI), involving data from baseline and at least one follow-up measure-
ment (N up to 1358, 47% males).
Results: Adolescent CRF was inversely, and regardless of adiposity, associ-
ated with middle age accumulated burden of cardiometabolic conditions in the
whole sample (N = 562, ß = −0.10, 95% confidence intervals [CI] [−0.18, −0.03],
p = 0.006), and elevated BP in females (N = 256, OR = 0.71, 95% CI [0.51, 0.91]).
Overall, we observed stronger associations in females than in males. An inverse
association of adolescent MF and SA with middle-aged WC was observed, but it
did not show as consistent associations as with CRF.
Conclusions: In this study, adolescent fitness, particularly CRF, was inversely as-
sociated with the burden of cardiometabolic conditions up to 45 years. Promotion
of fitness in youth may be beneficial in preventing adulthood cardiometabolic
diseases.