Chiari Syndrome: Advances in Epidemiology and Pathogenesis: A Systematic Review
Metadatos
Mostrar el registro completo del ítemAutor
Rodríguez Blanque, Raquel; Piqueras Sola, Beatriz; Sánchez García, Juan Carlos; Cortés Martín, JonathanEditorial
MDPI
Materia
Arnold Chiari Syndrome Arnold Chiari malformation Posterior cranial fossa Syringomyelia Hydrocephalus Scoliosis
Fecha
2023-10-23Referencia bibliográfica
Rodríguez-Blanque, R.; Almazán-Soto, C.; Piqueras-Sola, B.; Sánchez-García, J.C.; Reinoso-Cobo, A.; Menor-Rodríguez, M.J.; Cortés-Martín, J. Chiari Syndrome: Advances in Epidemiology and Pathogenesis: A Systematic Review. J. Clin. Med. 2023, 12, 6694. [https://doi.org/10.3390/jcm12206694]
Patrocinador
Official College of Nursing of Granada (CODEGRA); University of GranadaResumen
Arnold Chiari syndrome is a rare congenital disease of unknown prevalence and whose
origin is still under study. It is encompassed within the posterior cranial malformations, showing a
wide spectrum of symptomatology that can range from severe headache, dizziness, and paresthesia
to complete asymptomatology. It is for this reason that early diagnosis of the disease is difficult, and
it is usually diagnosed in adolescence. Treatment is based on remodeling and decompression of the
malformed posterior cranial fossa, although the risk of residual symptoms after surgery is high. The
aim of this review is to update all the existing information on this pathology by means of an exhaustive
analysis covering all the scientific literature produced in the last 5 years. In addition, it has been
carried out following the PRISMA model and registered in PROSPERO with code CRD42023394490.
One of the main conclusions based on the results obtained in this review is that the origin of the
syndrome could have a genetic basis and that the treatment of choice is the decompression of the
posterior cerebral fossa.