Discovery of pyrazolopyrimidines that selectively inhibit CSF-1R kinase by iterative design, synthesis and screening against glioblastoma cells

Baillache, Daniel J.; Valero Griñán, María Teresa; Lorente Macías, Álvaro; Bennett, David Jonathan; Elliott, Richard J. R.; Carragher, Neil O.; Unciti-Broceta, Asier

doi:10.1039/d3md00454f

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URI: https://hdl.handle.net/10481/85552

DOI: 10.1039/d3md00454f

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2023

Referencia bibliográfica

Baillache, D. J., Valero, T., Lorente-Macías, Á., Bennett, D. J., Elliott, R., Carragher, N., & Unciti-Broceta, A. (2023). Discovery of pyrazolopyrimidines that selectively inhibit CSF-1R kinase by iterative design, synthesis and screening against Glioblastoma cells. RSC Medicinal Chemistry.[DOI: 10.1039/d3md00454f]

Patrocinador

We are grateful to Medical Research Scotland (PHD-1046-2016) for funding and a joint Cancer Research UK (A28596) and The Brain Tumour Charity award (GN-000676) to N. O. C. T. V. thanks EU Horizon 2020 research and innovation programme under the Marie Skls PHD-1046-2016; Medical Research Scotland A28596; Cancer Research UK GN-000676; Brain Tumour Charity award 749299; European Union (EU); MSD

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