Variability Assessment of the Performance of MoS2-Based BioFETs
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Cuesta López, Juan; Toral López, Alejandro; González Marín, Enrique; García Ruiz, Francisco Javier; Pasadas Cantos, Francisco; Medina Rull, Alberto; Godoy Medina, AndrésEditorial
MDPI
Materia
BioFET MoS2 DNA Device-to-device variability Numerical modeling
Date
2023-01-10Referencia bibliográfica
Cuesta-Lopez, J... [et al.]. Variability Assessment of the Performance of MoS2-Based BioFETs. Chemosensors 2023, 11, 57. [https://doi.org/10.3390/chemosensors11010057]
Sponsorship
Spanish Government PID2020-116518GB-I00 TED2021-129769B-I00; FEDER/Junta de Andalucia A-TIC-646-UGR20 P20-00633; European Commission European Commission Joint Research Centre 825213; PAIDI 2020 grant 20804; PTA grant PTA2020-018250-I; Spanish Government FPU019/05132; Plan Propio of Universidad de GranadaAbstract
Two-dimensional material (2DM)-based Field-Effect Transistors (FETs) have been postulated
as a solid alternative for biosensing applications thanks to: (i) the possibility to enable chemical
sensitivity by functionalization, (ii) an atomically thin active area which guarantees optimal electrostatic
coupling between the sensing layer and the electronic active region, and (iii) their compatibility
with large scale fabrication techniques. Although 2DM-based BioFETs have demonstrated notable
sensing capabilities, other relevant aspects, such as the yield or device-to-device variability, will
demand further evaluation in order to move them from lab-to-fab applications. Here, we focus on
the latter aspect by analyzing the performance of MoS2-based BioFETs for the detection of DNA
molecules. In particular, we explore the impact of the randomized location and activation of the receptor
molecules at the sensing interface on the device response. Several sensing interface configurations
are implemented, so as to evaluate the sensitivity dependence on device-to-device variability