“There is nothing better than participating in this study”: Living the PAPAartis cardiovascular randomised controlled trial
Metadatos
Mostrar el registro completo del ítemEditorial
Elsevier
Fecha
2022-09-03Referencia bibliográfica
Nuria Romo-Avilés... [et al.]. “There is nothing better than participating in this study”: Living the PAPAartis cardiovascular randomised controlled trial, Contemporary Clinical Trials Communications, Volume 29, 2022, 100987, ISSN 2451-8654, [https://doi.org/10.1016/j.conctc.2022.100987]
Patrocinador
European Union’s Horizon 2020 733203Resumen
Qualitative research can bring new dimensions of understanding decision-making process in clinical trials. Participating in a randomized clinical trial requires
patients to accept complex information and make decisions in a context of uncertainty. It becomes especially complicated in the case of serious diseases in which the
treatment itself implies unknown risks. This study examines these issues in the context of the PAPAartis randomized clinical trial, which aims to prevent spinal cord
injuries that can occur as an adverse event following complex surgical repair of thoracoabdominal aneurysm. In this study, we accessed a group of 16 patients
participating in the trial and, through in-depth interviews, sought to understand the decision-making process when taking part in the trial and their experience of it.
Our results showed that patients participated for different reasons: due to trust in doctors, the hope of having a better treatment or for altruistic and collaborative
reasons with science. Many patients felt they did not fully understand the extraneous information provided about the study and the complex nature of the procedure.
Avoidance of paraplegia played a fundamental role in the decision to participate in this trial. Family support and the socioeconomic conditions of the patients
influenced the recovery process after surgery.