Inorganic Nanomaterials in Tissue Engineering
Metadatos
Mostrar el registro completo del ítemEditorial
MDPI
Materia
Nanomaterials Clays Bioceramics Magnetic nanoparticles Metal oxides Metallic nanoparticles Tissue engineering
Fecha
2022-05-26Referencia bibliográfica
Bianchi, E... [et al.]. Inorganic Nanomaterials in Tissue Engineering. Pharmaceutics 2022, 14, 1127. [https://doi.org/10.3390/pharmaceutics14061127]
Patrocinador
Horizon 2020 Research and Innovation Programme 814607Resumen
In recent decades, the demand for replacement of damaged or broken tissues has increased;
this poses the attention on problems related to low donor availability. For this reason, researchers
focused their attention on the field of tissue engineering, which allows the development of scaffolds
able to mimic the tissues’ extracellular matrix. However, tissue replacement and regeneration are
complex since scaffolds need to guarantee an adequate hierarchical structured morphology as well
as adequate mechanical, chemical, and physical properties to stand the stresses and enhance the
new tissue formation. For this purpose, the use of inorganic materials as fillers for the scaffolds has
gained great interest in tissue engineering applications, due to their wide range of physicochemical
properties as well as their capability to induce biological responses. However, some issues still need
to be faced to improve their efficacy. This review focuses on the description of the most effective
inorganic nanomaterials (clays, nano-based nanomaterials, metal oxides, metallic nanoparticles) used
in tissue engineering and their properties. Particular attention has been devoted to their combination
with scaffolds in a wide range of applications. In particular, skin, orthopaedic, and neural tissue
engineering have been considered.