The Effect of Dietary Polyphenols on Vascular Health and Hypertension: Current Evidence and Mechanisms of Action
Metadatos
Afficher la notice complèteEditorial
MDPI
Materia
Polyphenols Flavonoids Phenolic acids Hypertension Blood pressure Endothelial
Date
2022-01-27Referencia bibliográfica
Grosso, G... [et al.]. The Effect of Dietary Polyphenols on Vascular Health and Hypertension: Current Evidence and Mechanisms of Action. Nutrients 2022, 14, 545. [https://doi.org/10.3390/nu14030545]
Patrocinador
"Piano di incentivi per la ricerca di Ateneo 2020/2022" of the University of Catania, ItalyRésumé
The aim of this review was to explore existing evidence from studies conducted on humans
and summarize the mechanisms of action of dietary polyphenols on vascular health, blood
pressure and hypertension. There is evidence that some polyphenol-rich foods, including berry
fruits rich in anthocyanins, cocoa and green tea rich in flavan-3-ols, almonds and pistachios rich in
hydroxycinnamic acids, and soy products rich in isoflavones, are able to improve blood pressure
levels. A variety of mechanisms can elucidate the observed effects. Some limitations of the evidence,
including variability of polyphenol content in plant-derived foods and human absorption, difficulty
disentangling the effects of polyphenols from other dietary compounds, and discrepancy of doses
between animal and human studies should be taken into account. While no single food counteracts
hypertension, adopting a plant-based dietary pattern including a variety of polyphenol-rich foods is
an advisable practice to improve blood pressure.