Satellitome comparison of two oedipodine grasshoppers highlights the contingent nature of satellite DNA evolution
Metadatos
Mostrar el registro completo del ítemAutor
Martínez Camacho, Juan Pedro; Cabrero Hurtado, Josefa; López León, María Dolores; Martín Peciña, María; Perfectti Álvarez, Francisco; Garrido Ramos, Manuel Ángel; Ruiz-Ruano, Francisco J.Editorial
BioMed Central Ltd
Materia
Satellite DNA Library Hypothesis Satellitome Evolution Cytogenomics
Fecha
2022-02-07Referencia bibliográfica
Camacho, J.P.M., Cabrero, J., López-León, M.D. et al. Satellitome comparison of two oedipodine grasshoppers highlights the contingent nature of satellite DNA evolution. BMC Biol 20, 36 (2022). [https://doi.org/10.1186/s12915-021-01216-9]
Patrocinador
Marie Skłodowska-Curie 875732; Sven och Lilly Lawskis fond; European Commission; Uppsala Universitet; Centre for Interdisciplinary Mathematics, Uppsala UniversitetResumen
Background: The full catalog of satellite DNA (satDNA) within a same genome constitutes the satellitome. The
Library Hypothesis predicts that satDNA in relative species reflects that in their common ancestor, but the
evolutionary mechanisms and pathways of satDNA evolution have never been analyzed for full satellitomes. We
compare here the satellitomes of two Oedipodine grasshoppers (Locusta migratoria and Oedaleus decorus) which
shared their most recent common ancestor about 22.8 Ma ago.
Results: We found that about one third of their satDNA families (near 60 in every species) showed sequence
homology and were grouped into 12 orthologous superfamilies. The turnover rate of consensus sequences was
extremely variable among the 20 orthologous family pairs analyzed in both species. The satDNAs shared by both
species showed poor association with sequence signatures and motives frequently argued as functional, except for
short inverted repeats allowing short dyad symmetries and non-B DNA conformations. Orthologous satDNAs
frequently showed different FISH patterns at both intra- and interspecific levels. We defined indices of
homogenization and degeneration and quantified the level of incomplete library sorting between species.
Conclusions: Our analyses revealed that satDNA degenerates through point mutation and homogenizes through
partial turnovers caused by massive tandem duplications (the so-called satDNA amplification). Remarkably, satDNA
amplification increases homogenization, at intragenomic level, and diversification between species, thus
constituting the basis for concerted evolution. We suggest a model of satDNA evolution by means of recursive
cycles of amplification and degeneration, leading to mostly contingent evolutionary pathways where concerted
evolution emerges promptly after lineages split.